Feasibility of extracellular volume fraction calculation using myocardial CT delayed enhancement with low contrast media administration

Myocardial extracellular volume fraction (ECV) derived from CT delayed enhancement (CTDE) may allow assessment of diffuse myocardial fibrosis. However, the amount of contrast medium required for ECV estimation has not been established. Since ECV estimation by CT is typically performed in combination with coronary CT angiography (CCTA) in clinical settings, we aimed to investigate whether reliable ECV estimation is possible using the contrast dose optimized for CCTA without additional contrast administration.
Source: Journal of Cardiovascular Computed Tomography - Category: Radiology Authors: Source Type: research