Biological properties of a new mixed lanthanide(III) complex incorporating a dypiridinium ylide

Publication date: Available online 14 February 2020Source: Inorganica Chimica ActaAuthor(s): Aurel Tăbăcaru, Andreea Veronica Botezatu Dediu, Rodica Mihaela Dinică, Geta Cârâc, Vasile Basliu, Maria Paula Cabral Campello, Francisco Silva, Catarina I.G. Pinto, Joana F. Guerreiro, Marta Martins, Filipa Mendes, Fernanda MarquesAbstractA new mixed lanthanide(III) complex [LaNd(μ2-DPY)(μ4-SO4)2(Et3N)]Br2∙2H2O∙MeOH (La-Nd-DPY) was obtained by the reaction of N,N’-diphenacyl-4,4’-dipyridinium dibromide (DPB) with a mixture of La(III) and Nd(III) sulfates in a 2:1 molar ratio, in the presence of triethylamine (Et3N). The method used for the synthesis of La-Nd-DPY promoted the in situ transformation of the pro-ligand DPB into the dipyridinium ylide-based ligand. Fourier transform infrared spectroscopy (FTIR), elemental analysis (EA), thermogravimetric analysis (TGA) and mass spectrometry (MS) concurred to propose a linear polymeric structure for La-Nd-DPY, in which both La(III) and Nd(III) ions are six-coordinated. Cyclic voltammetry was also used to assess the redox potential of the mixed complex. Scanning electron microscopy (SEM) showed quite uniform and homogeneous fibrillary net-like morphology and also confirmed, by means of EDX analysis, the presence of both lanthanide (III) ions in the mixed complex. UV-vis absorption spectroscopy demonstrated that the mixed Ln complex is stable up to 1 h in DMSO and up to 72 h under the physiological conditions used for cell cul...
Source: Inorganica Chimica Acta - Category: Chemistry Source Type: research