Sustaining benefits of nutritional therapy in young adults with phenylketonuria - A 2 year prospective study
Publication date: March 2020Source: Molecular Genetics and Metabolism Reports, Volume 22Author(s): Johannes KrämerAbstractIntroductionPhenylketonuria (PKU) is an inborn error of metabolism, which is caused by a deficiency in the enzyme phenylalanine hydroxylase (PAH). Life-long Phe-free diet impairs quality of life, especially in adolescents and young adults which take responsibility over their diet and therapy from their parents, but expect freedom in daily routine.Methods and results105 patients with PKU were screened for eligibility for participating in this study. Data of 21 patients with genetic predictive value (GPV) ≤5 and age between 14 and 30 years were included in the analysis. Mean age of the study population was 22.6 ± 7.5 years, 8 patients (38%) were female. At baseline, structured counselling by a professional nutrionist was performed.Mean Phe-level at baseline was 926 ± 432 μmol/l, after six months Phe-levels were significantly reduced to 709 ± 314 μmol/l (p = .039), in total 4 additional patients (38% of the population) reached values within the therapeutic goal. After 12, 18 and 24 months, mean Phe-level elevated significantly to initial level (869 ± 427 μmol/l; p = .311). Mean daily intake of natural protein at baseline was 32.3 ± 24.3 g per day. There was a significant decrease after 6 months (26.9 ± 18.8 g/day; p = .049) and 12 months (25.9 ...
This study shows that ECE is a suitable dietary supplement candidate for the prevention or treatment of obesity or obesity-associated diseases, especially inflammation-related diseases. PMID: 32215011 [PubMed]
Publication date: Available online 27 March 2020Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Feiyan Liu, Yu Liu, Xizhuo Sun, Zhaoxia Yin, Honghui Li, Kunpeng Deng, Yang Zhao, Bingyuan Wang, Yongcheng Ren, Xuejiao Liu, Dongdong Zhang, Xu Chen, Cheng Cheng, Leilei Liu, Dechen Liu, Guozhen Chen, Shihao Hong, Chongjian Wang, Ming Zhang, Dongsheng Hu
Publication date: Available online 27 March 2020Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Kozo Okada, Kiyoshi Hibi, Yasuhiro Honda, Peter J. Fitzgerald, Kouichi Tamura, Kazuo Kimura
Publication date: Available online 27 March 2020Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Alvaro Alonso, Mary R. Rooney, Lin Yee Chen, Faye L. Norby, Amy K. Saenger, Elsayed Z. Soliman, Wesley T. O’Neal, Katie C. Hootman, Elizabeth Selvin, Pamela L. Lutsey
Publication date: May 2020Source: Journal of Functional Foods, Volume 68Author(s): Pinggui Wang, Xiang Gao, Yan Li, Shanglong Wang, Jia Yu, Yuxi Wei
CONCLUSION: A significant positive relationship was observed between sucrose in coffee and tea and the number of coronal or root caries lesions in community-dwelling elderly Japanese. PMID: 32212434 [PubMed - as supplied by publisher]
Publication date: Available online 27 March 2020Source: Molecular and Cellular EndocrinologyAuthor(s): Wenguang Chang, Hongge Fa, Dandan Xiao, Jianxun Wang
Publication date: Available online 27 March 2020Source: Diabetes &Metabolic Syndrome: Clinical Research &ReviewsAuthor(s): Roberto Laza-Cagigas, Shirley Chan, Daniel Sumner, Tarannum Rampal
Conclusion: This study showed moxibustion's ability to enhance the body's antioxidation and protect vascular endothelial function, thus playing an early role in the prevention and treatment of atherosclerosis. PMID: 32215035 [PubMed]
This study aimed to analyze the effects of Qihuang decoction combined with enteral nutrition on nutrition and the immune function of postoperative gastric cancer. Methods: 120 patients with postoperative gastric cancer in the study group and 117 in the control group were selected as the study subjects from our hospital at random. Indications of nutrition and immune and the rates of complications were compared the day before surgery and 1, 3, 7, and 14 days after surgery. Results: Indications of nutrition except hemoglobin (HB) in the study group were significantly higher than those before operation and the albumin ...