Induction of apoptosis increases sensitivity to detect cancer mutations in plasma
The study of cell-free DNA (cfDNA), namely the fraction derived from tumors (ctDNA), is a clinically relevant noninvasive biomarker for cancer management. However, the intrinsic low abundance of ctDNA in plasma limits its implementation in the clinic.
Source: European Journal of Cancer - Category: Cancer & Oncology Authors: Joana F. Marques, Susana Junqueira-Neto, Jorge Pinheiro, Jos é C. Machado, José L. Costa Tags: Original Research Source Type: research