Virus disinfection for biotechnology applications: Different effectiveness on surface versus in suspension.

In this study three liquid disinfectants, based on sodium hypochlorite, glutaraldehyde, or hydrogen peroxide/peroxyacetic acid, as well as one gaseous hydrogen peroxide-based disinfectant were investigated for inactivation of lipid enveloped and non-lipid enveloped model viruses, using suspension (for the liquid disinfectants) and carrier assay designs for their virucidal efficacy on surface. The results of these side-by-side investigations demonstrate that depending on the type of application, i.e. routine surface disinfection or decontamination of e.g. a contaminated bioreactor content, the most effective choice of disinfectant may be remarkably different.
PMID: 32057565 [PubMed - as supplied by publisher]

Source: Biologicals : Journal of the International Association of Biological Standardization - February 10, 2020 Category: Biotechnology Authors: Kindermann J, Karbiener M, Leydold SM, Knotzer S, Modrof J, Kreil TR Tags: Biologicals Source Type: research