Chinese sweet tea (Rubus suavissimus) polyphefnols attenuate the allergic responses in a Balb/c mouse model of egg allergy

Publication date: April 2020Source: Journal of Functional Foods, Volume 67Author(s): Yoshinori Mine, Kaustav Majumder, Yan Jin, Yuhan ZengAbstractThe aim of this study was to evaluate the effects of Rubus suavissimus S. Lee extract against hen egg ovalbumin (OVA)-induced allergic response in mice. BALB/c mice were sensitized with OVA via intraperitoneal injection for four weeks and subsequently administered the different doses of Rubus suavissimus S. Lee extract (0.1 0.5 and 1.0% w/v) in drinking water. We demonstrated that Rubus suavissimus S. Lee extract can attenuate OVA allergic response in mice by inducing immune desensitization through Th1/Th2 immunological modulation, a regulatory response involving the transcription factor FOXP3, induction of a suppressed IL-4, but increased IL-10, IL12a and INF-γ, enhanced immunoglobulin isotype IgA production, and suppression of histamine and MMCPT-1. These results suggest that Rubus suavissimus S. Lee extract may be a potentially useful candidate for the design of a functional food component in targeting management of food allergy.Graphical abstract
Source: Journal of Functional Foods - Category: Nutrition Source Type: research

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As the coronavirus spreads and locked-down communities stock up, products needed by allergy sufferers are increasingly hard to come by.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Peanuts Shopping and Retail Anaphylactic Shock Food Allergies Coronavirus (2019-nCoV) Labeling and Labels (Product) Supermarkets and Grocery Stores Epidemics Quarantines Stockpiling Food and Drug Administration United States Source Type: news
ConclusionThis guideline provides a  comprehensive guide to dietary counselling for food allergy by dietitians in Switzerland. It will inform best practice and improve patient-centred care and encourage a consistent approach, but it will need to be reviewed and updated as more robust evidence is produced.
Source: Allergo Journal International - Category: Allergy & Immunology Source Type: research
(Natural News) The effects of food allergies can range from simply being annoying or inconvenient, preventing you from eating your favorite food, to life-threatening, like difficulty breathing. While medical means of combating food allergies do exist, a recent study has found a more natural, and potentially more effective, method of fighting food allergies – adjusting...
Source: - Category: Consumer Health News Source Type: news
AbstractAllergic diseases are on the increase and can affect the child ’s well-being. The aim of this survey was to assess regional schools’ preparedness in dealing with anaphylaxis following the publication of national and international guidelines for schools in 2014. The survey was developed in 2015 and distributed to schools in Cumbria, North West England, UK be tween 2015 and 2016. Only 47% of the respondents (95% CI, 39–57%) felt confident to manage anaphylaxis. Schools without allergic pupils were significantly less likely to have a standard management protocol in place for emergencies compared to&n...
Source: European Journal of Pediatrics - Category: Pediatrics Source Type: research
Publication date: 4 April 2020Source: New Scientist, Volume 245, Issue 3276Author(s): Gege Li
Source: New Scientist - Category: Science Source Type: research
ConclusionThis work indicated the ability of LcZ to alleviate TM ‐induced food allergy and demonstrated the involvement of the tolerogenic immune cells and NF‐κB signaling pathway, indicating LcZ to be a potential immunomodulator and immunotherapy assistor.This article is protected by copyright. All rights reserved
Source: Molecular Nutrition and Food Research - Category: Food Science Authors: Tags: Research Article Source Type: research
Food allergy appears to have its roots in an insufficient exposure to a diverse range of environmental microbiota during early life. Microbial exposure ensures the colonization of the gastrointestinal tract wi...
Source: Clinical and Molecular Allergy - Category: Allergy & Immunology Authors: Tags: Review Source Type: research
Purpose of review The aim of the article is to critically appraise the most relevant studies in the rapidly advancing field of food allergy prevention. Recent findings Epidemiologic studies identified atopic dermatitis as a strong risk factor for food allergy, with mounting evidence for impaired skin barrier and cutaneous inflammation in the pathogenesis. Additional risk factors include a family history of atopy, the timing of allergenic food introduction into the infant's diet, dietary diversity, vitamin D, and environmental factors, such as dog ownership. Early introduction of allergenic foods (such as peanut) into ...
Source: Current Opinion in Clinical Nutrition and Metabolic Care - Category: Nutrition Tags: PAEDIATRICS: Edited by Berthold Koletzko and Raanan Shamir Source Type: research
AbstractThe panorama of food allergies (FA) has changed profoundly in recent years. In light of recent advances in knowledge of pathogenetic mechanisms and a greater attention to the multifaceted range of possible clinical manifestations, there is a need for a critical review of past classifications. Changes in nutrition, environment and lifestyles around the world are modifying the global FA epidemiology and new FA phenotypes are also emerging. Furthermore, both biotechnological advances in this field and recent personalized therapies have improved the diagnostic and therapeutic approach to FA. Consequently, both the prev...
Source: Archivum Immunologiae et Therapiae Experimentalis - Category: Allergy & Immunology Source Type: research
Publication date: Available online 31 March 2020Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Bruce T. Miles, Sofianne Gabrielli, Ann Clarke, Harley Eisman, Greg Shand, Moshe Ben-Shoshan
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
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