Isolation and whole genome sequencing of a new type of linezolid-resistant Enterococcus faecalis from two cases of infective endocarditis after renal transplantation
Publication date: Available online 13 February 2020Source: Journal of Global Antimicrobial ResistanceAuthor(s): Pengtao Bao, Zengzhen Zhang, Weiguo Zhao, Ying Jiang, Di Wang
Publication date: Available online 2 April 2020Source: European UrologyAuthor(s): Hui Zhang, Yan Chen, Quan Yuan, Qiu-Xiang Xia, Xian-Peng Zeng, Jing-Tao Peng, Jing Liu, Xing-Yuan Xiao, Guo-Song Jiang, Han-Yu Xiao, Liang-Bo Xie, Jing Chen, Jia-Li Liu, Xiong Xiao, Hua Su, Chun Zhang, Xiao-Ping Zhang, Hua Yang, Heng Li, Zhen-Di Wang
AbstractThese are the results of phase II study of bortezomib-melphalan-prednisolone (VMP) induction therapy followed by lenalidomide-dexamethasone (Rd) consolidation and lenalidomide maintenance in transplant-ineligible patients with newly diagnosed multiple myeloma (NDMM). The primary end point was progression-free survival (PFS). Secondary end points included overall survival (OS), overall response rates (ORRs), and safety. Eighty-three eligible patients were enrolled between October 2012 and August 2014. The median PFS was 28.0 months (95% CI 19.6–36.7) and the median OS was 55.3 months (95% CI 51.6&nd...
Conclusions. Although there is an association between malignancy and IE, no treatment strategy has yet been developed for these patients. Short-term outcome of IE is unaltered by cancer. In most papers, the effect of cancer on mid-term survival is only significant in a univariate analysis, without being a predictor. The results indicate that cardiac surgery for IE should not be withheld in patients in whom a treatable malignancy has been found. PMID: 32233824 [PubMed - in process]
In conclusion, this ESRI technique combined with MRI, may offer a powerful clinical tool to noninvasively detect variable hypoxic status in tumors and to identify a window of vascular renormalization to maximize the effects of combination therapy with antiangiogenic drugs. PMID: 32238677 [PubMed - as supplied by publisher]
Publication date: Available online 2 April 2020Source: Journal of Global Antimicrobial ResistanceAuthor(s): Pengcheng Du, Dejun Liu, Huangwei Song, Pei Zhang, Ruichao Li, Yulin Fu, Xiao Liu, Jinli Jia, Xiaodi Li, Séamus Fanning, Yang Wang, Li Bai, Hui Zeng
Conditions: Asymptomatic Bacteriuria; Kidney Transplant Infection Intervention: Diagnostic Test: Urinary culture and treatment if asymptomatic bacteriuria is detected Sponsor: Centenario Hospital Miguel Hidalgo Recruiting
Authors: Temmerman F, Laleman W, Maleux G, Nevens F Abstract Patients with hepatic encephalopathy (HE) do not systematically receive priority on the waiting list for liver transplantation. In some patients with cirrhosis, excessive amounts of gut derived ammonia can bypass the liver parenchyma due to large spontaneous portosystemic shunts (SPSS) induced by portal hypertension. A similar but iatrogenic condition can occur after transjugular portosystemic shunt (TIPS) insertion. In these situations HE may develop and can become refractory to standard management. In patients with preserved liver function, embolization...
CONCLUSION: This case highlights the utility of LT as a viable treatment option for acute sickle cell intrahepatic cholestasis. PMID: 32231764 [PubMed]
Authors: Zhang ZY, Wang ZM, Huang Y Abstract Polycystic liver disease (PLD) is a rare hereditary disease that independently exists in isolated PLD, or as an accompanying symptom of autosomal dominant polycystic kidney disease and autosomal recessive polycystic kidney disease with complicated mechanisms. PLD currently lacks a unified diagnostic standard. The diagnosis of PLD is usually made when the number of hepatic cysts is more than 20. Gigot classification and Schnelldorfer classification are now commonly used to define severity in PLD. Most PLD patients have no clinical symptoms, and minority with severe compli...
Publication date: March 2020Source: Journal of Global Antimicrobial Resistance, Volume 20Author(s): Pengtao Bao, Zengzhen Zhang, Weiguo Zhao, Ying Jiang, Di Wang