Antimicrobial stewardship in patients with acute bacterial skin and skin structures infections: an international Delphi consensus
ConclusionsThis Delphi survey provided useful indicators for the implementation of antimicrobial stewardship principles in the clinical management of ABSSSI and offers interesting elements of discussion about the barriers existing in Europe for the optimal implementation of antimicrobial stewardship programs.
CONCLUSION: These compounds can be used alone or with FDA approved drugs to overcome biofilm related K. pneumoniae and S. aureus infections. PMID: 32238140 [PubMed - as supplied by publisher]
Authors: González-Martín M, Alberto Corbera J, Suárez-Bonnet A, Tejedor-Junco MT Abstract Coagulase-positive Staphylococci (CoPS) can exist as commensals in humans, companion and food-producing animals, but can cause severe or even lethal diseases. Exchange of these bacteria between humans and animals has been described. Special attention has been focused on Methicillin-Resistant Staphylococcus aureus, but other CoPS can also represent an important threat. In addition to significant antimicrobial resistance, these bacteria may carry a plethora of virulence factors - molecules that allow bacteri...
Staphylococcus aureus is a primary pathogen of orthopedic infections. By mediating antimicrobial resistance, S. aureus biofilm plays an important role in the recalcitrance of orthopedic infections, especially for...
In conclusion, the ePlex BCID-GP Panel compares favorably to SOC and targeted molecular methods for the identification of 20 Gram-positive pathogens and four antimicrobial resistance genes in positive blood culture bottles. This panel detects a broad range of pathogens and mixed infections with yeast and Gram-negative organisms from the same positive blood culture bottle.
This study shows that phosphonopeptides, including alafosfalin, may have a therapeutic role to play in an era of increasing antibacterial resistance.
Publication date: Available online 19 March 2020Source: Journal of Global Antimicrobial ResistanceAuthor(s): Ryo Nomura, Hidemasa Nakaminami, Kotaro Takasao, Shuna Muramatsu, Yuji Kato, Takeaki Wajima, Norihisa Noguchi
Conclusion. Data produced on the propensity of a molecule to induce bacterial resistance is useful and appropriate when launching a new preservative. PMID: 32186482 [PubMed - as supplied by publisher]
This study aimed to describe the rates and molecular mechanisms of mupirocin resistance in clinicalStaphylococcus aureus isolates from Tygerberg Hospital, and to describe its association with strain types.MethodsWe retrospectively selected 212 S. aureus isolates which were identified from blood samples and pus swabs during the years 2009 –2011 and 2015–2017. The isolates were identified using conventional microbiological methods and genotyping was done usingspa typing. Cefoxitin (30 μg) disc diffusion and the two disc strategy (5 μg and 200 μg) were used to determine susce...
Publication date: Available online 10 March 2020Source: Journal of Global Antimicrobial ResistanceAuthor(s): Sol Romina Martínez, Virginia Aiassa, Claudia Sola, María Cecilia Becerra
Publication date: Available online 10 March 2020Source: Journal of Global Antimicrobial ResistanceAuthor(s): Raziey Parastan, Mohammad Karga, Kavous Solhjoo, Farshid Kafilzadeh