Genetic polymorphism in MDR1 C3435T is a determinant of methotrexate cerebrospinal fluid concentrations in Chinese children with acute lymphoblastic leukemia .

CONCLUSION: This study showed that the polymorphism of MDR1 C3435T influenced the CSF concentration of MTX in patients with Chinese childhood ALL receiving IV and IT HDMTX treatment. . PMID: 32053102 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32053102?dopt=Abstract

Source: International Journal of Clinical Pharmacology and Therapeutics - February 15, 2020 Category: Drugs & Pharmacology Tags: Int J Clin Pharmacol Ther Source Type: research

Genetic polymorphism in MDR1 C3435T is a determinant of methotrexate cerebrospinal fluid concentrations in Chinese children with acute lymphoblastic leukemia .

Genetic polymorphism in MDR1 C3435T is a determinant of methotrexate cerebrospinal fluid concentrations in Chinese children with acute lymphoblastic leukemia .