Lumateperone: First Approval

This article summarizes the milestones in the development of lumateperone leading to this first approval for the treatment of schizophrenia.
Source: Drugs - Category: Drugs & Pharmacology Source Type: research

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You're reading Overcoming Your Former Self: Small Steps Toward Higher Self-Esteem, originally posted on Pick the Brain | Motivation and Self Improvement. If you're enjoying this, please visit our site for more inspirational articles. When analyzing the driving factor behind your decisions, there is one common denominator that many people overlook: self-esteem. Self-esteem is a reflection of your perceived value. If you do not have a positive self-image, your motivation to achieve great things diminishes. Because of this, it is important to work on empowering yourself to better actionize your goals. People suffering fro...
Source: PickTheBrain | Motivation and Self Improvement - Category: Consumer Health News Authors: Tags: confidence featured psychology self-improvement self esteem self improvement Source Type: blogs
Publication date: Available online 5 April 2020Source: Journal of Psychiatric ResearchAuthor(s): Chengchao Zuo, Huan Cao, Fengfei Ding, Jianling Zhao, Yaqi Huang, Guo Li, Shanshan Huang, Hong Jiang, Yongsheng Jiang, Furong Wang
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research
Publication date: Available online 5 April 2020Source: Journal of Psychiatric ResearchAuthor(s): Christian Eric Deuter, Katja Wingenfeld, Christian Otte, Jasmin Bustami, Michael Kaczmarczyk, Linn Kristina Kuehl
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research
Authors: Pu M, Wang X, Zhang J Abstract An increasing body of research has focused on the functions of the glutamate receptor ionotropic kainate 4 (GRIK4) gene in treatment for depression, memory, as well as neurodegenerative diseases. It is widely recognized that major depressive disorder (MDD) patients often display cognitive dysfunctions, which do not strictly correlate with the severity of depressive symptoms, and in some individuals persist after clinical remission. However, little is known regarding the particular role of GRIK4 in cognitive functions of patients suffering from a MDD. The current study therefo...
Source: Revue Neurologique - Category: Neurology Tags: Rev Neurol (Paris) Source Type: research
(Natural News) Keeping your immune system strong and healthy is important since it protects you from germs that can make you sick. There are many ways to boost your immunity, such as eating nutritious foods, taking vitamin supplements and exercising regularly. Getting enough sleep each night is also key to supporting immune health and overall...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
Authors: Kang JH, Kim MH, Lee HJ, Huh JW, Lee HS, Lee DS Abstract High concentrations of glutamate induce neurotoxicity by eliciting reactive oxygen species (ROS) generation and intracellular Ca2+ influx. The disruption of Ca2+ homeostasis in the endoplasmic reticulum (ER) evokes ER stress, ultimately resulting in neuronal dysfunction. Additionally, glutamate participates in the development of neurodegenerative diseases, such as Alzheimer's and Parkinson's diseases. Peroxiredoxins (Prxs) are members of a family of antioxidant enzymes that protect cells from neurotoxic factor-induced apoptosis by scavenging hydrogen...
Source: Free Radical Research - Category: Research Tags: Free Radic Res Source Type: research
I was offered an out of match fellowship position and accepted it 2 days ago. Now, due to family issues It would not be ideal for me to relocate to that area. Is there a way I can withdraw my acceptance (I haven’t sign the intent letter or anything whatsoever, just email agreement) or would it be profesional suicide?
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Anesthesiology Source Type: forums
Publication date: Available online 4 April 2020Source: Aggression and Violent BehaviorAuthor(s): Scott Harcourt
Source: Aggression and Violent Behavior - Category: Psychiatry & Psychology Source Type: research
Authors: Annette S, Stephan G, Mueser KT, Martin H, Elisabeth R, Ulrich G, Marketa C, Rolf E, Hans-Jürgen M, Peter F Abstract Neuropsychological functioning turns out to be a rate-limiting factor in psychiatry. However, little is known when comparing neuropsychological and psychosocial functioning in inpatients with schizophrenia or severe depression in their treatment pathways including add-on psychoeducation or the latter combined with cognitive behavioral therapy up to 2-year follow-up. To evaluate this question, we investigated these variables in two randomised controlled trials including 196 patients with...
Source: European Archives of Psychiatry and Clinical Neuroscience - Category: Psychiatry Tags: Eur Arch Psychiatry Clin Neurosci Source Type: research
CONCLUSION: This N-of-1 study suggests the Emerald device is feasible to use and can potentially yield actionable data regarding behavioral symptom management. No active or potential device risks were encountered. PMID: 32245677 [PubMed - as supplied by publisher]
Source: The American Journal of Geriatric Psychiatry - Category: Psychiatry Tags: Am J Geriatr Psychiatry Source Type: research
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