Fertility preservation outcomes in women with gliomas: a retrospective case –control study

AbstractPurposeWith advances in cancer therapy, reproductive-aged women can look forward to a life post-malignancy. Fortunately, fertility preservation (FP) may provide relief from potential infertility caused by cancer or associated caustic treatments. Outcomes of FP in pre-treatment reproductive-aged women with gliomas have not been previously characterized.MethodsBetween 2007 and 2018, 10 patients undergoing FP prior to chemotherapy and/or radiation treatment for gliomas were identified at Brigham and Women ’s Hospital. They were matched 3:1 to male-factor infertility patients by age ± 1 year.ResultsPatients with gliomas had significantly lower baseline anti-M üllerian hormone levels than male-factor infertility controls (2.37 vs 5.16 ng/mL,p  =  0.002, log transformed). Despite higher starting (350 vs. 240 IU,p = 0.004) and total gonadotropin doses (4270 vs. 2270 IU,p  
Source: Journal of Neuro-Oncology - Category: Cancer & Oncology Source Type: research

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Source: Oncology Letters - Category: Cancer & Oncology Tags: Oncol Lett Source Type: research
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Source: Oncology Letters - Category: Cancer & Oncology Tags: Oncol Lett Source Type: research
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Source: Oncology Letters - Category: Cancer & Oncology Tags: Oncol Lett Source Type: research
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Source: Oncology Letters - Category: Cancer & Oncology Tags: Oncol Lett Source Type: research
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Source: Oncology Letters - Category: Cancer & Oncology Tags: Oncol Lett Source Type: research
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Source: Oncology Letters - Category: Cancer & Oncology Tags: Oncol Lett Source Type: research
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Source: Oncology Letters - Category: Cancer & Oncology Tags: Oncol Lett Source Type: research
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