A novel DNA damage response signature of IDH-mutant grade II and grade III astrocytoma at transcriptional level

ConclusionWe developed a two-gene signature which can effectively predict the prognosis of patients with IDH-mutant grade II and grade III astrocytoma. It suggests a novel classification of astrocytoma with better prognostic accuracy based on the expression of DNA damage response genes.
Source: Journal of Cancer Research and Clinical Oncology - Category: Cancer & Oncology Source Type: research