Fast MRI sequences for clarification of acute neurological symptoms.

[Fast MRI sequences for clarification of acute neurological symptoms]. Radiologe. 2020 Feb 12;: Authors: Wenger KJ, Hattingen E Abstract CLINICAL/METHODICAL ISSUE: Neurological symptoms account for approximately 30% of emergency room (ER) visits. Clinical outcome often relies on a timely diagnosis and treatment initiation. Clinical imaging requirements are fast availability and high diagnostic value. STANDARD RADIOLOGICAL METHODS: Availability and quality of magnetic resonance imaging (MRI) in emergency rooms outside of core hours are limited compared to computed tomography (CT). Common reasons are infrastructural accessibility (hospitals using outpatient radiology centers), a lack of experienced and qualified staff and high patient compliance requirements. However, in a neurological emergency setting, MRI may show relevant advantages over CT in certain areas, such as diagnosis of stroke. METHODOLOGICAL INNOVATIONS: Advances in MRI technology have led to shorter exam times and robust motion reduction strategies. Common fast sequences and time reduction techniques for imaging of neurological emergencies are presented in this article. ACHIEVEMENTS: Recommendations for specific sequences or techniques depend on the institute's MRI hardware and software components. If available, parallel imaging is highly recommended for imaging of neurological emergencies. PRACTICAL RECOMMENDATIONS: Imaging of neurological emergencies requ...
Source: Der Radiologe - Category: Radiology Authors: Tags: Radiologe Source Type: research

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Conditions:   Ischemic Stroke;   Hemorrhagic Shock Intervention:   Radiation: Brain magnetic resonance imaging (MRI) , computed tomography (CT) Sponsor:   Assiut University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
ConclusionLower LMR was independently related to higher risk of HT in patients with AIS. Admission LMR may be used as one of the predictors for HT. Further prospective multicenter studies are needed to validate our findings.
Source: Neurological Sciences - Category: Neurology Source Type: research
Abstract OBJECTIVE: We performed a meta-analysis to evaluate the agreement of cardiac computed tomography (CT) with cardiac magnetic resonance imaging (CMRI) in the assessment of right ventricle (RV) volume and functional parameters. MATERIALS AND METHODS: PubMed, EMBASE, and Cochrane library were systematically searched for studies that compared CT with CMRI as the reference standard for measurement of the following RV parameters: end-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV), or ejection fraction (EF). Meta-analytic methods were utilized to determine the pooled weighted bias, lim...
Source: Korean J Radiol - Category: Radiology Authors: Tags: Korean J Radiol Source Type: research
AbstractMost of the acute ischemic events, such as acute coronary syndromes and stroke, are attributed to vulnerable plaques. These lesions have common histological and pathophysiological features, including inflammatory cell infiltration, neo-angiogenesis, remodelling, haemorrhage predisposition, thin fibrous cap, large lipid core, and micro-calcifications. Early detection of the presence of a plaque prone to rupture could be life-saving for the patient; however, vulnerable plaques usually cause non-haemodynamically significant stenosis, and anatomical imaging techniques often underestimate, or may not even detect, these ...
Source: Annals of Nuclear Medicine - Category: Nuclear Medicine Source Type: research
CONCLUSION: Through combining anatomical, metabolic imaging and behavioral studies, our study provides evidence of neuroprotective effects of HT in NAIS. These results are potentially translational to human NAIS. PMID: 32115740 [PubMed - as supplied by publisher]
Source: International Journal of Developmental Neuroscience - Category: Neuroscience Authors: Tags: Int J Dev Neurosci Source Type: research
AbstractBackgroundAtrial myxoma remains a rare clinical entity with an incidence of surgically resected cases of 0.5 –0.7 per million population and prevalence of
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
CONCLUSION: In summary, the method applied to nCT scans performed in the acute stage of stroke provided robust and accurate information about brain lesions' location and size, as well as quantitative values. We found that nCT and VBQ analyses areeffective for identifying neural signatures of concomitant language impairments at the individual level, and neuroanatomical maps of aphasia at the population level. The signatures explicate the neurophysiological mechanisms underlying aetiology of the stroke. Ultimately, similar analyses with larger cohorts could lead to a more integrated multimodal model of behavior and brain ana...
Source: Current Topics in Medicinal Chemistry - Category: Chemistry Authors: Tags: Curr Top Med Chem Source Type: research
We report the case of a 14-year-old girl who presented with right-sided weakness and ataxia, loss of sensation, and altered mental status. Magnetic resonance imaging with diffusion-weighted imaging showed an acute lesion in the distribution of the left posterior cerebral artery, and magnetic resonance angiogram demonstrated occlusion of the third branch of the left posterior cerebral artery. With parental consent, clinicians decided to infuse an adult dose of weight-adjusted intravenous alteplase at 3.5 hours from onset of symptoms, with subsequent improvement in National Institutes of Health Stroke Scale score from 11 to ...
Source: Pediatric Emergency Care - Category: Emergency Medicine Tags: Illustrative Cases Source Type: research
AbstractAimsThe study assessed 4 ‐year outcomes of intramyocardial injections of autologous bone marrow‐derived mesenchymal stromal cells (MSCs) in patients with ischaemic heart failure.Methods and resultsThe MSC ‐HF trial was a randomized, double‐blind, placebo‐controlled trial. Patients were randomized 2:1 to intramyocardial injections of MSCs or placebo. The primary endpoint was change in left ventricular end‐systolic volume (LVESV), measured by magnetic resonance imaging or computed tomography. S ixty patients aged 30–80 years with ischaemic heart failure, New York Heart Association class II&nd...
Source: European Journal of Heart Failure - Category: Cardiology Authors: Tags: Research Article Source Type: research
AbstractEarly neurological deterioration (END) following intravenous recombinant tissue plasminogen activator (rt-PA) treatment is a serious clinical event that can be caused by hemorrhagic or ischemic insult. We investigated the differences in predictive factors for END due to hemorrhagic and END due to ischemic insults. Consecutive patients from four hospitals who received 0.6  mg/kg intravenous rt-PA for acute ischemic stroke were retrospectively recruited. END was defined as a National Institutes of Health Stroke Scale (NIHSS) score ≥ 4 points within 24 h compared with baseline. END was class...
Source: Journal of Thrombosis and Thrombolysis - Category: Hematology Source Type: research
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