Management of Infected Bone Defects of the Lower Extremities by Three-Stage Induced Membrane Technique.
CONCLUSIONS TSIMT is effective in treating infected bone defects of the lower extremities. Advanced age, longer duration of infected bone defects, active smoking, and external fixation adversely affect bone union and recovery of infected extremities in a limited time span. PMID: 32047141 [PubMed - in process]
Conclusions: Despite the various advantages of the delayed tolerance induction protocol, it failed to reliably induce mixed chimerism and thus immunologic tolerance to vascularized composite allografts, given currently available immunosuppression treatment options. Ongoing work shows promise in overcoming these limitations.
Conclusion: PRP treats ONFH mainly through three mechanisms: inducing angiogenesis and osteogenesis to accelerate bone healing, inhibiting inflammatory reactions in necrotic lesions, and preventing apoptosis induced by glucocorticoids. In addition, as an adjunctive therapy for core decompression, the use of PRP is recommended to improve the treatment of early-stage ONFH patients, especially when combined with stem cells and bone grafts, by inducing osteogenic activity and stimulating the differentiation of stem cells in necrotic lesions. PMID: 32219128 [PubMed - as supplied by publisher]
CONCLUSION: Patients take most pain medication during the first postoperative week after adolescent ACLR, although patient and surgical variables had no notable influence on pill consumption. LEVEL OF EVIDENCE: Level IV, case series. PMID: 32213778 [PubMed - in process]
Primary graft dysfunction (PGD), defined as the presence of lung allograft infiltrates consistent with pulmonary edema and hypoxemia, is a devastating early complication of lung transplantation (1). PGD is a major risk factor for poor outcomes after lung transplant including death and development of chronic lung allograft dysfunction (CLAD) (2-4). Numerous studies have defined clinical risk factors for PGD (4) and there is extensive literature studying mechanisms of ischemia-reperfusion injury in experimental model systems (5).
Publication date: Available online 28 March 2020Source: Journal of OrthopaedicsAuthor(s): Hee-Gon Park, Hee-Jeong Ham
Shelf acetabuloplasty continues to be effective in the prevention or delay of osteoarthritis in adolescent dysplastic hips. We aimed to evaluate the efficacy and to determine the correct level of the bone graft objectively. We retrospectively analyzed 16 hips underwent Shelf acetabuloplasty originated by Spitzy. The mean age at surgery was 15.3 years old with the mean caput index at 39.7%. The average follow-up was 11 years. The radiological evaluation was based on acetabular-head index (AHI) at preoperative and latest radiographs, acetabular-Shelf distance (ASD) and Shelf-head ratio at immediate postoperative and latest r...
Conclusions: Through this systemic review and meta-analysis, no significant difference was found with regards to fusion rate, postoperative NDI, and VAS between tantalum fusion and iliac crest bone graft in ACDF. More longer-term and randomized studies with large samples are warranted to validate any association found in this study. Level of Evidence: Level II.
Condition: Alveolar Bone Resorption Intervention: Procedure: Horizontal alveolar bone augmentation Sponsors: October 6 University; Ain Shams University Completed
Publication date: Available online 25 March 2020Source: Journal of OrthopaedicsAuthor(s): M. Sakti, K.T. Biakto, M.A. Usman, M.J. Tedjajuwana, P. Pasallo, E.S. Subagio
AbstractIntroductionResults of iterative ACL reconstructions are lower than after primary reconstructions. Our aim was to report the results of a retrospective series of revision using pedicled quadruple hamstring autograft. The hypothesis was that the results were satisfactory and comparable to the literature.MethodsThe study period was from January 2012 to December 2014. Fourteen patients (average age 26) were included. A fascia lata graft was used 12 times for primary reconstruction. Trauma was the cause of failure 12 times. The time interval between primary reconstruction and revision was 6.2 years. Preoperative ...