Downregulation of MiR-218-5p Protects Against Oxygen-Glucose Deprivation/Reperfusion-Induced Injuries of PC12 Cells via Upregulating N-myc Downstream Regulated Gene 4 (NDRG4).

CONCLUSIONS</strong> Downregulation of miR-218-5p protect against OGDR-induced injuries of PC12 cells through reducing inflammatory cytokines secretion, oxidative stress status, apoptosis rate and maintenance of endovascular homeostasis via upregulating NDRG4. MiR-218-5p may serve as a novel effective biomarker to monitor AIS progression. PMID: 32048632 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/32048632?dopt=Abstract

Source: Medical Science Monitor - February 14, 2020 Category: Research Tags: Med Sci Monit Source Type: research