CEAP clinical classes C0S-C4: differences, similarities and place of Ruscus+HMC+VitC in treating patients with chronic venous disease.

CEAP clinical classes C0S-C4: differences, similarities and place of Ruscus+HMC+VitC in treating patients with chronic venous disease. Int Angiol. 2020 Feb 12;: Authors: Kakkos SK, Guex JJ, Lugli M, Nicolaides AN Abstract Since the publication of the CEAP classification, new research has enriched our knowledge; notably on the heritability of CVD and the genetic and environmental factors involved in this condition, as well as the symptoms apparent within the spectrum of the CEAP clinical classes and the benefits of medical treatment. Using the CEAP classification as a special theme, a symposium entitled "CEAP Clinical Classes C0S-C4: Differences, Similarities and Place of Ruscus+HMC+VitC in Treating Patients with CVD" was held at the annual meeting of the 2019 European Venous Forum. The lectures presented much valuable information, from which some key points can be extracted. The influence of environmental factors was demonstrated, and the fact that a large amount of information can be obtained from comprehensive history taking. There is robust evidence for heritability. Many candidate genes/loci have been identified, potentially offering new targets for treatment. More research is needed, notably using genome-wide association studies and also on microbiota, which may play a role in CVD through the inflammation pathway. Ruscus+HMC+VitC acts by increasing venous and lymphatic tone, protecting microcirculation, and reducing inflammation...
Source: International Angiology - Category: Cardiology Tags: Int Angiol Source Type: research