THBS1 facilitates colorectal liver metastasis through enhancing epithelial-mesenchymal transition.
CONCLUSIONS: By collecting the omics data with functional studies, the present results reveal that THBS1 facilitates colorectal liver metastasis through promoting epithelial-mesenchymal transition. This understanding of molecular roles of THBS1 in CRLM may be promising to develop targeted therapies to prolong survival in CRC patients.
PMID: 32052380 [PubMed - as supplied by publisher]
Source: Clinical Colorectal Cancer - Category: Cancer & Oncology Authors: Liu X, Xu D, Liu Z, Li Y, Zhang C, Gong Y, Jiang Y, Xing B Tags: Clin Transl Oncol Source Type: research
More News: Cancer | Cancer & Oncology | Colorectal Cancer | Databases & Libraries | Epithelial Cancer | Liver | Study | Urology & Nephrology