Protective immunity elicited by the nematode-conserved As37 recombinant protein against < i > Ascaris suum < /i > infection

Conclusions/SignificanceAs37 is anA.suum expressed immunodominant antigen that elicited significant protective immunity in mice when formulated with AddaVax™. As37 is highly conserved in other STHs, but not in humans, suggesting it could be further developed as a pan-helminth vaccine against STH co-infections.
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research