Oral Manifestations and Challenges in Dental Treatment of Epidermolysis Bullosa Dystrophica

Source: Journal of Dentistry for Children - Category: Dentistry Authors: Tags: Case Reports Source Type: research

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Experimental Dermatology,Volume 0, Issue ja, -Not available-.
Source: Experimental Dermatology - Category: Dermatology Authors: Source Type: research
Condition:   Recessive Dystrophic Epidermolysis Bullosa Intervention:   Biological: EB-101 Sponsors:   Jean Yuh Tang;   Abeona Therapeutics, Inc Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
British Journal of Dermatology, EarlyView.
Source: British Journal of Dermatology - Category: Dermatology Authors: Source Type: research
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Letters to the Editor Source Type: research
Journal of the European Academy of Dermatology and Venereology, EarlyView.
Source: Journal of the European Academy of Dermatology and Venereology - Category: Dermatology Authors: Source Type: research
CONCLUSIONS: In summary, our data demonstrate that trans-splicing-mediated mRNA therapy is an effective method for the correction of dominantly inherited KRT14 mutations at the transcriptional level. This results in the rescue of the EBS-gen sev phenotype and a stabilization of the epidermis in a xenograft mouse model. This article is protected by copyright. All rights reserved. PMID: 30099737 [PubMed - as supplied by publisher]
Source: The British Journal of Dermatology - Category: Dermatology Authors: Tags: Br J Dermatol Source Type: research
British Journal of Dermatology,Volume 0, Issue ja, -Not available-.
Source: British Journal of Dermatology - Category: Dermatology Authors: Source Type: research
CONCLUSION: The treatment of skin diseases based on topical delivery of siRNA, which act by inhibiting the expression of target transcripts, offers many potential therapeutic advantages for suppressing genes into the skin. PMID: 30084329 [PubMed - as supplied by publisher]
Source: Current Pharmaceutical Design - Category: Drugs & Pharmacology Authors: Tags: Curr Pharm Des Source Type: research
The Journal of Dermatology, EarlyView.
Source: The Journal of Dermatology - Category: Dermatology Authors: Source Type: research
Journal of Cellular Physiology, EarlyView.
Source: Journal of Cellular Physiology - Category: Cytology Authors: Source Type: research
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