Oral Manifestations and Challenges in Dental Treatment of Epidermolysis Bullosa Dystrophica

Source: Journal of Dentistry for Children - Category: Dentistry Authors: Tags: Case Reports Source Type: research

Related Links:

Epidermolysis bullosa (EB) is a group of hereditary skin diseases characterized by widespread blister formation from birth. The recessive dystrophic EB (RDEB) subtype is caused by mutations in the COL7A1 gene, which encodes type VII collagen, the main protein that forms anchoring fibrils beneath the dermal-epidermal junction (DEJ) [1 –3]. There are no established therapies, only symptomatic treatments; therefore, extensive research has been conducted in search of effective treatments. Candidates for fundamental treatments are cell-based therapies, including allogeneic mesenchymal stem/stromal cell (MSC)-based therapi...
Source: Journal of Dermatological Science - Category: Dermatology Authors: Source Type: research
Conclusions Skin reduction with deepithelialization and tissue infolding preserves dermal plexus perfusion and promotes nipple and skin flap survival in immediate implant-based and autologous breast reconstruction after SSM and NSM. This technique can be combined with NAC devascularization to further promote nipple perfusion. Overall, this method offers an acceptable complication rate and the potential to expand the reconstructive options available to women with large and/or ptotic breasts.
Source: Annals of Plastic Surgery - Category: Cosmetic Surgery Tags: Breast Surgery Source Type: research
Publication date: Available online 8 June 2018 Source:Actas Dermo-Sifiliográficas (English Edition) Author(s): A. Imbernón-Moya, R. Maseda-Pedrero, M. Feito, R. de Lucas
Source: Actas Dermo-Sifiliograficas - Category: Dermatology Source Type: research
Functional lumen imaging probe (FLIP) uses high-resolution impedance planimetry to measure the cross-sectional area along an axial plane during a volume-controlled distension. FLIP evaluates the mechanical properties of the esophageal lumen and dynamic parameters including the cross-sectional area (CSA), compliance, diameter, and distensibility index (a calculated value based on the smallest CSA divided by the pressure needed to maintain the smallest CSA). EsoFLIP ® is one variant of the FLIP that in addition to providing luminal data also allows stricture dilation.
Source: Gastrointestinal Endoscopy - Category: Gastroenterology Authors: Tags: Tuesday abstract Source Type: research
Condition:   Dystrophic Epidermolysis Bullosa Intervention:   Biological: KB103 Sponsor:   Krystal Biotech, Inc. Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Dystrophic Epidermolysis Bullosa Intervention:   Biological: Topical KB103 Sponsor:   Krystal Biotech, Inc. Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Dystrophic Epidermolysis Bullosa Intervention:   Biological: KB103 Sponsor:   Krystal Biotech, Inc. Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Dystrophic Epidermolysis Bullosa Intervention:   Biological: Topical KB103 Sponsor:   Krystal Biotech, Inc. Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Dystrophic Epidermolysis Bullosa Intervention:   Biological: KB103 Sponsor:   Krystal Biotech, Inc. Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Dystrophic Epidermolysis Bullosa Intervention:   Biological: Topical KB103 Sponsor:   Krystal Biotech, Inc. Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
More News: Children | Dentistry | Epidermolysis Bullosa