Predicting autism risk may begin with a drop of blood

(University of California - San Diego) A novel research study by UC San Diego researchers will determine whether testing stored blood drops, recorded at birth, for 1,000 different molecules and chemicals can help predict autism risk years before symptoms would likely appear.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news

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Publication date: Available online 6 April 2020Source: Brain, Behavior, and ImmunityAuthor(s): Fangna Yin, Hongbing Wang, Zeya Liu, Junwei Gao
Source: Brain, Behavior, and Immunity - Category: Neurology Source Type: research
An unprecedented new study deepens the understanding of the genetic triggers that lead to conditions like autism spectrum disorder and schizophrenia.
Source: Yale Science and Health News - Category: Universities & Medical Training Source Type: news
The hypothalamus–pituitary–adrenal (HPA) axis acts to release cortisol into the blood stream, as cortisol calls the body into action to combat stress. When high amounts of cortisol interact with the hypothalamus, the HPA axis will slow down its activity. The amygdala detects stress, while the prefrontal cortex regulates our reactions to stress. Source: Bezdek K and Telzer E (2017) Have No Fear, the Brain is Here! How Your Brain Responds to Stress. Front. Young Minds. 5:71. doi: 10.3389/frym.2017.00071 _______ [Editor’s note: Continued from yesterday’s Exploring the human brain and how it responds to...
Source: SharpBrains - Category: Neuroscience Authors: Tags: Cognitive Neuroscience Education & Lifelong Learning Health & Wellness #WorldHealthDay brain burnout cognition Cortisol GAS General Adaptation Syndrome homeostasis memory neurobiology neurological exhaustion Stress Source Type: blogs
(Yale University) From early prenatal development through childhood, the prefrontal cortex of the human brain undergoes an avalanche of developmental activity. In some cases, it also contains seeds of neuropsychiatric illnesses such as autism spectrum disorder and schizophrenia, according to a new genetic analysis led by researchers at Yale University and the University of California-San Francisco.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
Conclusions: Results indicate that maternal thyroid conditions are associated with increased ASD risk in progeny, but suggestively not due to direct effects of thyroid hormones. Instead, factors that influence maternal thyroid function could have etiologic roles in ASD through pathways independent of maternal gestational thyroid hormones and thus be unaffected by medication treatment. Factors known to disrupt thyroid function should be examined for possible involvement in ASD etiology.
Source: Epidemiology - Category: Epidemiology Tags: Women’s Health Source Type: research
Individuals with autism spectrum disorder (ASD) are often behaviorally hyper-reactive to light touch, but it is unclear to what degree this arises from a fundamental sensory difference vs. higher order systems for attention or emotion processing. Thus far, experimental findings for light touch detection are mixed, and few previous studies have independently considered sensitivity (the ability to discriminate signal from noise) and decision criterion (the overall response bias or tendency to answer “yes” or “no” in a detection task). We tested a large sample of children, adolescents, and adults with ...
Source: Frontiers in Human Neuroscience - Category: Neuroscience Source Type: research
AbstractEfforts to identify the causes of autism spectrum disorders have highlighted the importance of both genetics and environment, but the lack of human models for many of these disorders limits researchers ’ attempts to understand the mechanisms of disease and to develop new treatments. Induced pluripotent stem cells offer the opportunity to study specific genetic and environmental risk factors, but the heterogeneity of donor genetics may obscure important findings. Diseases associated with unusuall y high rates of autism, such asSCN2A syndromes, provide an opportunity to study specific mutations with high effect...
Source: Molecular Autism - Category: Molecular Biology Source Type: research
In addition to all the worry and uncertainty in the midst of the COVID-19 pandemic, Vanessa Coens is concerned about her two boys with autism regressing during this period of self-isolation.
Source: CBC | Health - Category: Consumer Health News Tags: News/Canada/Windsor Source Type: news
Autistic individuals experience elevated risk for suicide ideation, attempts, and deaths. Little is known about how clinicians assess risk or intervene with suicidal autistic individuals. We surveyed 121 clinicians about use of suicide prevention practices...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
hello all!! I am just looking for any advice/guidance I can get. But my plan didn’t work out this year so I am planning on re-applying in 2021. My undergraduate GPA is 3.5 and science is 3.2. And I got 497 on MCAT. I am definitely going to retake the MCAT. I am trying to figure out how to best stay productive and use the next two years to my advantage to set my application apart. I currently work at a great company as a registered behavioral technician with children with autism. I am... GAP YEAR advice please!!!
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Re-Applicants [ MD / DO ] Source Type: forums
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