Sexually Dimorphic DNA-methylation in Cardiometabolic Health: A Systematic Review

Cardiometabolic diseases include cardiovascular diseases (CVD), type 2 diabetes (T2D) and their associated risk factors including components of the metabolic syndrome and obesity[1]. Aging is associated with development of unfavorable cardiometabolic profile which in large contributes to increased incidence of major cardiovascular events and mortality[2]. Intermediate cardiometabolic risk factors are unequally distributed among sexes, and sex differences are also described in cardiometabolic diseases prevalence, clinical characteristics and prognosis[3 –5].

Source: Maturitas - February 12, 2020 Category: Primary Care Authors: Eralda Asllanaj, Xiaofang Zhang, Carolina Ochoa Rosales, Jana Nano, Wichor M. Bramer, Eliana Portilla-Fernandez, Kim V.E. Braun, Valentina Gonzalez-Jaramillo, Wolfgang Ahrens, Arfan Ikram, Mohsen Ghanbari, Trudy Voortman, Oscar H. Franco, Taulant Muka, Ma Source Type: research