Different source of commercial vegetable oils may regulate metabolic, inflammatory and redox status in healthy rats

Publication date: March 2020Source: Journal of Functional Foods, Volume 66Author(s): Sttefany Viana Gomes, Bruna Vidal Dias, Renata Rebeca Pereira, Karine de Pádua Lúcio, Débora Maria Soares de Souza, André Talvani, Geraldo Célio Brandão, Gustavo Pereira Cosenza, Karina Barbosa de Queiroz, Daniela Caldeira CostaAbstractOur goal was to carry out a comparative study to evaluate the metabolic and inflammatory effects and the redox status of commercial vegetable oils supplementation [linseed (LO), coconut (VCO), and sunflower (SO)] in metabolically healthy rats. The results found in this study showed that the LO group decreased the HOMA-IR and hepatic cholesterol, and increased the serum levels of IL-6. Supplementation with VCO increased glucose and HOMA-IR, cholesterol concentration and serum triacylglycerol (TAG). In this group, there was also an increase in TBARS. In the SO group there was a decrease in serum concentrations of cholesterol and TAG and an increase in hepatic concentration of these lipids. In addition, in the SO group there was a decrease in hepatic and serum concentrations of IL-6 and hepatic levels of TNF, as well as a decrease in the GSH/GSSG ratio, suggesting changes in glutathione metabolism and inflammatory mediators.Graphical abstract
Source: Journal of Functional Foods - Category: Nutrition Source Type: research