Deletion of macrophage migration inhibitory factor ameliorates inflammation in mice model severe acute pancreatitis

ConclusionOur data provided strong evidence for the participation of MIF in the pathogenesis of AP and subsequent inflammatory response. The genetic ablation of MIF or its inhibition with pharmacological agents significantly ameliorated the severity of AP.
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research