An overview of drug discovery efforts for eczema: why is this itch so difficult to scratch?

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Source: Expert Opinion on Drug Discovery - Category: Drugs & Pharmacology Authors: Source Type: research

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CONCLUSION: As vulvar pruritus has multiple causes, standard- ization of its diagnostic evaluation and treatment would be l efficacy and to meet the diverse needs of women who suffer from this condition. PMID: 32181734 [PubMed - in process]
Source: Deutsches Arzteblatt International - Category: General Medicine Tags: Dtsch Arztebl Int Source Type: research
Abstract BACKGROUND: Little is known about the measurement properties of Patient-Oriented Scoring Atopic Dermatitis (PO-SCORAD) in adults with AD. Even less is known about how PO-SCORAD performs compared to the Patient-Oriented Eczema Measure (POEM). OBJECTIVE: To examine the measurement properties of PO-SCORAD and compare them with POEM. METHODS: A prospective dermatology-practice based study of 291 AD patients (age 1872 years). RESULTS: PO-SCORAD and POEM were moderately correlated with each other (Spearman rho=0.56); had weak-moderate correlations with Numeric Rating Scale (NRS) worst-itch and av...
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Ann Allergy Asthma Immunol Source Type: research
ECZEMA is a condition where patches of skin become inflamed, red, itchy, cracked and rough. The condition can negatively affect one's life. What is the best treatment that can help relieve the symptoms of eczema?
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
ECZEMA is an unsightly condition whereby flare-ups lead to red, dry and itchy skin - which is most definitely not the look people are after. A study reveals a golden spice could help relieve symptoms of the skin disorder.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Abstract BACKGROUND: Sleep disturbances (SD) are common in adults with atopic dermatitis (AD). Patient-Reported Outcomes Measurement Information System (PROMIS™) SD and Sleep-Related Impairment (SRI) are validated questionnaires to assess sleep in adults. Little is known about their measurement properties in adults with AD. OBJECTIVE: To assess the measurement properties of PROMIS SD and SRI 8-item short-forms in AD. METHODS: We performed a prospective dermatology practice-based study using questionnaires and evaluation by a dermatologist (n=420). RESULTS: PROMIS SD/SRI showed moderate correla...
Source: The British Journal of Dermatology - Category: Dermatology Authors: Tags: Br J Dermatol Source Type: research
Atopic eczema is a relapsing, itchy chronic cutaneous inflammatory disease that commonly affects children. The disease is often complicated by cutaneous infections such as eczema herpeticum, eczema vaccinatum ...
Source: BMC Dermatology - Category: Dermatology Authors: Tags: Case report Source Type: research
CONCLUSIONS: We found lack of evidence to address our review question: for most of our interventions of interest, we found no eligible studies. The neurokinin 1 receptor (NK1R) antagonist serlopitant was the only intervention that we could assess. One study provided low-certainty evidence suggesting that serlopitant may reduce pruritus intensity when compared with placebo. We are uncertain of the effects of serlopitant on other outcomes, as certainty of the evidence is very low. More studies with larger sample sizes, focused on patients with CPUO, are needed. Healthcare professionals, patients, and other stakeholders may h...
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Tags: Cochrane Database Syst Rev Source Type: research
CONCLUSIONS: While the use of CAP for disinfection and wound treatment has already moved into clinical practice, further applications such as cancer treatment are still exploratory. PMID: 31965204 [PubMed - as supplied by publisher]
Source: Der Hautarzt: Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete - Category: Dermatology Tags: Hautarzt Source Type: research
BEST supplements eczema: Eczema is a condition where patches of skin become inflamed, itchy, red, cracked and rough. The condition is extremely uncomfortable for the person suffering with it, however there could be a supplement that helps cure the symptoms.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
ConclusionsFindings from this literature review and in-depth qualitative interviews supported the development of a comprehensive conceptual model documenting the signs, symptoms and impacts relevant to CHE patients. Such a model is of considerable value given the lack of existing studies in the literature focused on the qualitative exploration of the CHE patient experience. Limitations included the patient sample being only from the US and not including some CHE subtypes.
Source: Advances in Therapy - Category: Drugs & Pharmacology Source Type: research
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