Suppressive role of Viola odorata extract on malignant characters of mammosphere-derived breast cancer stem cells

ConclusionViola odorata extract exerted anti-cancerous activity on both breast cancer cell lines and their derived BCSCs. Anti-cancerous activity of this extract was significantly more in MCF7-, SKBR3-derived mammospheres in comparison with dedicated cell lines. Data suggest thatViola odorata extract mostly targets cancerous cells, not normal cells with exception in high concentration. It acts in a cell-dependent manner.
Source: Clinical and Translational Oncology - Category: Cancer & Oncology Source Type: research