Bariatric Surgery May Cut Risk for Colorectal Cancer in Obese Patients

Relative risk for developing colorectal cancer reduced by about 35 percent with bariatric surgery for obesity
Source: The Doctors Lounge - Oncology - Category: Cancer & Oncology Tags: Gastroenterology, Oncology, Surgery, Journal, Source Type: news

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THURSDAY, March 12, 2020 -- Patients with obesity undergoing bariatric surgery have the same risk for colorectal cancer (CRC) as the general population, according to a study published online March 11 in JAMA Surgery. Laurent Bailly, M.D., Ph.D.,...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
In an analysis of more than one million patients, researchers report that obese adults who meet the criteria for bariatric surgery, but don't undergo it, are 34 percent more likely to be diagnosed with colorectal cancer.
Source: Health News - UPI.com - Category: Consumer Health News Source Type: news
This nationwide cohort study conducted using the French national health insurance information system database assesses whether undergoing bariatric surgery is associated with altered risk of colorectal cancer among individuals with obesity.
Source: JAMA Surgery - Category: Sports Medicine Source Type: research
In this issue of JAMA Surgery, Bailly et al report on the association of incident colorectal cancer (CRC) risk with bariatric surgery in a large sample of surgical and nonsurgical patients from the French National Health Insurance Information System. Using multivariable propensity score matching, they report a hazard ratio (HR) of 0.68 (95% CI, 0.60-0.77) for CRC when comparing patients undergoing bariatric surgery with matched nonsurgical patients. When the expected-to-observed CRC rates in the bariatric surgery group and matched nonsurgical patients were compared with the general population, the standardized incidence ra...
Source: JAMA Surgery - Category: Sports Medicine Source Type: research
Obese adults who undergo bariatric surgery may face a greater risk of colon cancer than their peers who don't have weight-loss surgery, a new study in a large Nordic cohort suggests.Reuters Health Information
Source: Medscape General Surgery Headlines - Category: Surgery Tags: Hematology-Oncology News Source Type: news
ConclusionsVery low energy diets result in a clinically significant reduction in mesorectal fat with a lesser change in total pelvic fat, suggesting that very low energy diets may be useful for preparation for pelvic surgery in the obese. The distance from S1 to the posterior rectum correlates well with mesorectal reduction, making this a valuable clinical tool when volumetric analysis is not possible.  This analysis is limited to the quantification of the effect of the diet and cannot comment on the safety of this approach before pelvic cancer surgery.
Source: Techniques in Coloproctology - Category: Surgery Source Type: research
Obesity is a risk factor for colorectal cancer and possibly the formation of precancerous, colorectal polyps . Bariatric surgery is very effective for long-term weight loss; however, it is not known whether bariatric surgery decreases the risk of subsequent colonic neoplasia. We hypothesized that bariatric surgery would decrease the risk of developing colorectal lesions (new cancer and precancerous polyps).
Source: Surgery - Category: Surgery Authors: Source Type: research
Katherine Samaras1,2,3*, Henrik Tevaerai4, Michel Goldman5, Johannes le Coutre6,7 and Jeff M. P. Holly8 1Department of Endocrinology, St Vincent's Hospital, Darlinghurst, NSW, Australia 2Diabetes and Metabolism, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia 3St Vincent's Hospital, St Vincent's Clinical School, Darlinghurst, NSW, Australia 4Bern University Hospital, Bern, Switzerland 5Institute for Interdisciplinary Innovation in Healthcare, Universite Libre de Bruxelles, Bruxelles, Belgium 6Department of Medicine, Imperial College London, London, United Kingdom 7Nes...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Conclusions: Bariatric surgery appears to be capable of partially reversing the obesity-related epigenome. The identification of potential epigenetic biomarkers predictive for the success of bariatric surgery may open new doors to personalized therapy for severe obesity. Introduction Obesity is currently a huge healthcare problem, worldwide, and is a risk factor for several diseases such as type 2 diabetes (T2D), cardiovascular disease and cancer (1). As the prevalence of obesity reaches pandemic proportions, this metabolic disease is estimated to become the biggest cause of mortality in the near future (2). In fact,...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Dr Lowenfels comments on a study that suggests weight loss surgery may lower the risk for obesity-associated cancers (endometrial, colon, pancreatic, and postmenopausal breast).Medscape General Surgery
Source: Medscape Today Headlines - Category: Consumer Health News Tags: General Surgery Viewpoint Source Type: news
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