Serological evidence of Toxoplasma gondii infection as potential risk for the development of lepromatous leprosy in an endemic area for both neglected tropical diseases in Brazil

ConclusionsAltogether, our results suggest thatT. gondii infection may exert immunomodulatory properties that influence to the susceptibility of leprosy, mainly on its more severe clinical form. A better understanding of parasite immunomodulation can ultimately contribute to the development of medical applications.
Source: Infectious Diseases of Poverty - Category: Infectious Diseases Source Type: research

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Publication date: 6 June 2020Source: New Scientist, Volume 246, Issue 3285Author(s): Michael Marshall
Source: New Scientist - Category: Science Source Type: research
Conclusion: Significant consensus in the perception of complications was observed in most of the analyzed scenarios for both LA and NA. However, within the LA data, responses to different clinical scenarios varied. PMID: 32494370 [PubMed]
Source: Surgical Neurology International - Category: Neurosurgery Tags: Surg Neurol Int Source Type: research
Publication date: Available online 4 June 2020Source: Brazilian Journal of OtorhinolaryngologyAuthor(s): Selçuk Yildiz, Harun Karaca, Sema Zer Toros
Source: Brazilian Journal of Otorhinolaryngology - Category: ENT & OMF Source Type: research
Publication date: Available online 4 June 2020Source: Brazilian Journal of OtorhinolaryngologyAuthor(s): Liang Jiwang, Luo Yahong, Liang Kai, Huang Bo, Zhao Yuejiao, Wang Haotian, Yu Tao
Source: Brazilian Journal of Otorhinolaryngology - Category: ENT & OMF Source Type: research
Abstract In the Philippines, ten NTDs are prevalent, but only six namely LF, schistosomiasis, STH, food-borne trematodiases, rabies and leprosy are considered to be of public health importance. The 81 provinces in the country are endemic for at least one of these NTDs. Others may be endemic for two or even more of these diseases. Since 2000, after the Philippines accepted and implemented the WHO guidelines for NTDs prevention, control and elimination, significant progress has been achieved in reducing the magnitude of NTDs endemic in the country". Since 2009, out of 46 filariasis-endemic provinces, the number...
Source: Acta Tropica - Category: Infectious Diseases Authors: Tags: Acta Trop Source Type: research
CONCLUSION: This study suggests that the surrounding environment (soil and water) of leprosy patients contain viable M. leprae and the viability has association with Acanthamoeba which may provide a protective niche for M. leprae. This could play an important role in the focal transmission of the disease. PMID: 30658215 [PubMed - as supplied by publisher]
Source: Infection, Genetics and Evolution - Category: Genetics & Stem Cells Authors: Tags: Infect Genet Evol Source Type: research
Leprosy is a chronic infectious disease that primarily affects peripheral nerves, and the skin, but can also compromise functions of the eyes and other organs. Mycobacterium leprae (M. leprae) is the etiological agent and an obligate intracellular parasite [1]. Leprosy remains a serious public health problem in developing countries, such as India, Brazil and Indonesia, and it is endemic in Africa, Asia and Latin America [2].
Source: Journal of Dermatological Science - Category: Dermatology Authors: Source Type: research
Growing up a musically-obsessed child in the 80's, Daryl Hall was one of my biggest inspirations. A masterful, inventive songwriter with an ocean of soul, he set me on the path to being an artist, to never waste a word, and to sing because I mean it. With six number ones and five additional top ten hits throughout the 70's and 80's Daryl Hall and John Oates are the number one duo in music history. Still at the top of his game at 69 years old, Daryl has won legions of new fans with his hit MTV Live show Live From Daryl's House. In February of 2015, at my very sickest from chronic Lyme and Bartonella, after it was missed b...
Source: Science - The Huffington Post - Category: Science Source Type: news
Conclusion: Post-kala-azar dermal leishmaniasis is a rare dermal complication of VL that mimics leprosy and should be considered particularly in countries where both diseases are endemic. A co-infection must be seriously considered, especially in patients who are non-responsive to treatment or develop persistent leprosy reactions as those encountered in the patient reported here.
Source: BMC Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research
Conclusions: Trend analysis of reported new detection rates from India does not support a thesis of rapid progress in leprosy control.
Source: Parasites and Vectors - Category: Microbiology Authors: Source Type: research
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