RAS Pathway Mutation Patterns in Patients with Juvenile Myelomonocytic Leukemia; A developing country single center experience
Juvenile Myelomonocytic Leukemia (JMML) is a rare hematological malignancy. Developing countries are lagging behind in their facilities in molecular diagnostics. The bone marrow for 41 Egyptian children treated as JMML were retrospectively studied for RAS mutations. Mutations were detected in 80% of patients. Cancer centers in our region should start implementing molecular diagnostics before confirming the diagnosis of JMML.
Source: Clinical Lymphoma, Myeloma and Leukemia - Category: Hematology Authors: Nayera Hamdy, Hossam Bokhary, Amr Elsayed, Walaa Hozayn, Sonya Soliman, Sherine Salem, Khaled Alsheshtawi, Amr Abdallah, Hanafy Hafez, Mahmoud Hammad Tags: Original Study Source Type: research
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