Anti-Saccharomyces cerevisiae Immunogloblin G and Immunoglobulin A antibodies are associated with systemic inflammation and advanced disease in hidradenitis suppurativa

This is the first prospective study showing that ASCA are biomarkers for HS, especially in severe inflammatory forms, but not in PV, supporting the contribution of a gut fungal dysbiosis to HS pathogenesis.

Source: Journal of Allergy and Clinical Immunology - February 13, 2020 Category: Allergy & Immunology Authors: Florence Assan, Jeremy Gottlieb, Florence Tubach, Said Lebbah, Nicolas Guigue, Geoffroy Hickman, Emeline Pape, Marine Madrange, Emmanuel Delaporte, Boualem Sendid, Fran çois Aubin, Francis Derouin, Stéphane Bretagne, Pascal Richette, Asma Smahi, Emilie Source Type: research