Precise treatment of acute antibody-mediated cardiac allograft rejection in rat using C4d targeted microbubbles loaded with nitric oxide

Over the past four decades, cardiac transplantation has achieved considerable success in patients with end-stage heart disease; however, the incidence of antibody-mediated rejection (AMR) remains high and is considered to be an important cause of life-threatening cardiac allograft dysfunction.1-3

Source: The Journal of Heart and Lung Transplantation - February 13, 2020 Category: Transplant Surgery Authors: Tao Liao, Qiaojia Li, Yannan Zhang, Zhe Yang, Zhengyu Huang, Fei Han, Xiaolong Chen, Tinghui Yin, Jie Ren, Qiquan Sun Tags: Original Pre-Clinical Science Source Type: research