Solvent directed discrimination of metal ions using a coumarin-pyridine fluorescence receptor

Publication date: Available online 10 February 2020Source: Sensors and Actuators B: ChemicalAuthor(s): Zhiyuan Cao, Xia Fan, Zhiyu Yang, Xuebin Zhang, Ningxujin Ding, Yubin Ding, Weihua ZhangAbstractThe development of reliable methods for large scale discrimination of versatile metal ions is meaningful to avoid metal poisoning accidents and investigate their biological roles. Herein, a solvent directed strategy is reported for readily construction of a robust and powerful fluorescent sensor array R1SA for effective metal ion discrimination. The four sensors of R1SA were obtained by simply dissolving a unique coumarin-pyridine compound R1 in four different solvents, i.e., methanol, ethanol, acetonitrile and DMSO respectively. The sensing mechanism was based on the fact that R1 showed fluorescence responses towards various metal ions in a solvent directed manner. R1SA was able to generate distinct fluorescence response patterns for 12 kinds of metal ions including Cd2+, Co2+, V3+, Sn2+, Fe3+, Cr3+, Hg2+, Mn2+, Cu2+, Bi3+, Pb2+, and Ag+. It was able to discriminate these 12 metal ion species reliably in both aqueous solution and serum media, and identify the unknown metal ion in serum samples with high accuracy. Moreover, R1SA was also successfully applied to discriminate metal ion mixtures of Sn2+/Pb2+, Cd2+/Hg2+ and the valence states of iron in water and 5% serum media, indicating that it can be considered as a practical tool for investigating the biological roles of iron.Gra...
Source: Sensors and Actuators B: Chemical - Category: Chemistry Source Type: research