Risk factors for earlier dementia onset in autopsy-confirmed Alzheimer's disease, mixed Alzheimer's with Lewy bodies, and pure Lewy body disease.

DISCUSSION: Male sex and APOE ɛ4 alleles increase risk for earlier dementia onset in AD but not LBD. Depression increases risk for earlier dementia onset in AD, LBD, and AD + LBD, but evaluating the course, treatment, and severity is needed in future studies. PMID: 32043803 [PubMed - as supplied by publisher]
Source: The Journal of Alzheimers Association - Category: Psychiatry Tags: Alzheimers Dement Source Type: research

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It is increasingly recognized that there is significant heterogeneity in phenotype and clinical trajectories in Alzheimer's disease as well as Lewy Body and Vascular dementia. Relatively common neurodegenerative disorder, Lewy Body Dementia (LBD) presents with psychiatric features. Mood disorders are common and often precede core symptoms of LBD. Patient with LBD especially early in the course of disease are at increased risk for suicide. Psychosis is one of the most debilitating symptoms of LBD as it is an independent risk factor for nursing home placements, increased caregiver distress and mortality.
Source: The American Journal of Geriatric Psychiatry - Category: Geriatrics Authors: Tags: Session 304 Source Type: research
Journalist and filmmaker Max Lugavere has committed his life to exploring and understanding brain health, prompted by the loss of his mom to dementia that began at the unusually young age of 58. His newest book, Genius Life: Heal Your Mind, Strengthen Your Body, and Become Extraordinary, has just been released. Written with genuine heartfelt passion and attention to detail, Max has crafted a wonderful book for anyone interested in understanding how to preserve brain health and bolster brain performance. Here is an excerpt from the especially well-crafted chapter he calls “The Vigor Trigger”: Ice, Ice, Baby Prio...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Open avoid cognitive decline brain health can Alzheimers be prevented can dementia be prevented cognition lugavere preserve cognition prevent Alzheimers prevent dementia Source Type: blogs
AbstractPurpose of ReviewDementia is a progressive brain disease that affects 5.8 million people in the USA. In 2018, more than 16 million Americans provided unpaid care for persons with dementia (PWD). Most of this care is provided by family members and friends yielding 18.5 billion hours of unpaid care worth $233.9 billion.Novel technological approaches to assist caregivers and improve health and function of PWD are being explored. Models to assess and predict behaviors may provide greater quality of life (QOL) for both PWD and their caregivers. The purpose of this paper is to review current available technologies for be...
Source: Current Geriatrics Reports - Category: Geriatrics Source Type: research
Photo credit Berhard Grossgasteiger The truth, as they see it, is still the truth in their eyes. Delusions, hallucinations, agitation, aggression, and depression are all part of the gradual progression of psychosis of patients with Alzheimer ’s disease (AD). An average of 41% of these patients will experience these psychotic symptoms. One of the most common delusions these patients have is theft-related. An experienced caregiver offers her advice on how to deal with accusations of theft, which are common in dementia patients. Continue reading on Agingcare to learn more about the frustration and pain of being falsely ...
Source: Minding Our Elders - Category: Geriatrics Authors: Source Type: blogs
In conclusion, this meta-analysis indicated that group exercises improve cognition, attention and executive function in community-dwelling older adults with mild cognitive impairment or Alzheimer's disease. PMID: 32191630 [PubMed - as supplied by publisher]
Source: Aging - Category: Biomedical Science Authors: Tags: Aging (Albany NY) Source Type: research
It’s 3 pm on a warm, sunny Saturday. For the past 20 years your mother would dress in her finest clothes and walk to her neighbor’s house for her weekly bridge game. For the past month, however, she has not been interested in playing bridge. Although she sometimes required prompting (as well as reminders to brush her hair), she usually returned from these games cheerful. Her indifference this month is new. Your mother received the diagnosis of mild Alzheimer’s disease last year. Although visibly frustrated at times, especially when she cannot think of the right word or find her pocketbook, she seemed to e...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Alzheimer's Disease Behavioral Health Caregiving Healthy Aging Mental Health Source Type: blogs
CONCLUSION: The present study provides preliminary evidence that aMCI patients may benefit from a cognitive intervention program based on re-experiencing recent autobiographical events. However, future studies incorporating a control group will be needed to confirm these preliminary findings. PMID: 32183672 [PubMed - as supplied by publisher]
Source: Current Alzheimer Research - Category: Neurology Authors: Tags: Curr Alzheimer Res Source Type: research
It is increasingly recognized that there is significant heterogeneity in phenotype and clinical trajectories in Alzheimer's disease as well as Lewy Body and Vascular dementia. Relatively common neurodegenerative disorder, Lewy Body Dementia (LBD) presents with psychiatric features. Mood disorders are common and often precede core symptoms of LBD. Patient with LBD especially early in the course of disease are at increased risk for suicide. Psychosis is one of the most debilitating symptoms of LBD as it is an independent risk factor for nursing home placements, increased caregiver distress and mortality.
Source: The American Journal of Geriatric Psychiatry - Category: Geriatrics Authors: Tags: BRIDGING THE GAP BETWEEN NEUROLOGY AND PSYCHIATRY- PSYCHIATRIC SYMPTOMS IN THE COURSE OF NEURODEGENERATIVE DISORDERS Source Type: research
Progressive supranuclear palsy is a taupathy disorder often mistaken on diagnosis by other neurocognitive disorders such as Parkinson's (PD) and Alzheimer's (AD) disease amongst other. PSP tends to be diagnosed in the later course of the disease and by time of diagnosis, individuals have a median survival of 7?years. PSP is a disease in which a diagnosis and treatment is done in a multidisiplinary approach involving collaboration of Psychiatry and Neurology. As it was seen in this clinical case which describes a patient with undetected progressive supranuclear palsy who were referred to a university hospital psychiatric em...
Source: The American Journal of Geriatric Psychiatry - Category: Geriatrics Authors: Tags: Poster Number: EI-36 Source Type: research
Over 5.8?million people in the US are currently living with Alzheimer's disease (AD), the most common form of neurodegenerative dementia. More than 90% of individuals with AD experience neuropsychiatric symptoms (NPS), such as agitation, apathy, and depression. Agitation is one of the most common NPS, which not only accounts for 12% of health and social care costs but also increases the risk of mortality and caregiver burden. The most common treatments for agitation include psychotropic medications, used off-label, along with behavioral management strategies.
Source: The American Journal of Geriatric Psychiatry - Category: Geriatrics Authors: Tags: Poster Number: NR - 29 Source Type: research
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