Restless legs syndrome among multiple sclerosis patients in lebanon

ConclusionRestless legs syndrome is commonly found among patients with multiple sclerosis in Lebanon, is underdiagnosed, and ought to be systematically evaluated for in order to improve the patients’ quality of life.
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research

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Abstract Restless legs syndrome (RLS) is a sleep disorder that may exacerbate many of the symptoms and consequences of multiple sclerosis (MS), and may have further implications for health-related quality of life (HRQOL). The present study examined the relationships among RLS, symptoms and HRQOL in people with MS. Participants with MS (n = 275) completed the Cambridge-Hopkins Restless Legs Syndrome Questionnaire, the International Restless Legs Syndrome Study Group Scale, the Multiple Sclerosis Impact Scale, the Pittsburgh Sleep Quality Index, the Fatigue Severity Scale, the Hospital Anxiety and Depressi...
Source: Journal of Sleep Research - Category: Sleep Medicine Authors: Tags: J Sleep Res Source Type: research
ConclusionCompared to HCs, individuals with NMOSD reported poorer quality of life and higher levels of depression and anxiety. Further, among individuals with NMOSD, sleep characteristics are predicted by a complex variety of illness-related factors.
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research
Multiple sclerosis (MS) is related to the demyelination of intracranial nerves at multiple sites, while restless legs syndrome (RLS) appears to be caused by dysfunction of the dopaminergic system. Since RLS prevalence is higher among MS patients than in the general population, we carried out an updated meta-analysis to understand whether the two diseases might be associated.
Source: Sleep Medicine - Category: Sleep Medicine Authors: Tags: Original Article Source Type: research
Authors: Giannaki CD, Aristotelous P, Stefanakis M, Hadjigeorgiou GM, Manconi M, Leonidou E, Sakkas GK, Pantzaris M Abstract Objectives Restless legs syndrome (RLS) symptoms are common in Multiple Sclerosis (MS) patients. The aim of the current study was to examine for the first time whether RLS could affect the functional capacity and various contributing parameters related to quality of life and fatigue in MS patients. Methods According to their RLS status, 50 relapsing-remitting MS patients were divided into the RLS (n = 10) and non-RLS groups (n = 40). Specific questionnaires were used in or...
Source: Neurological Research - Category: Neurology Tags: Neurol Res Source Type: research
Introduction and objectives: Patients with multiple sclerosis (MS) frequently have unrecognized sleep disorders at higher frequency than the general population. Sleep disorders such as insomnia, sleep related breathing disorder (SBD), periodic limbs movement disorder (PLMD), REM sleep behavior disorder (RBD), narcolepsy and restless legs syndrome (RLS) have been reported; these processes are related to fatigue and poor quality of life in these patients. We aimed to identify the presence of sleep disorders in 60 patients diagnosed with MS and to analyze the demographic and clinical findings of that subpopulation presenting both pathologies.
Source: Sleep Medicine - Category: Sleep Medicine Authors: Tags: Other Source Type: research
Patients with multiple sclerosis (MS) are at increased risk for comorbid sleep disturbances, which can profoundly contribute to poor functional status and fatigue. Insomnia, sleep-disordered breathing, and restless legs syndrome are among the most common sleep disorders experienced by patients with MS. Despite their impact, these underlying sleep disorders may escape routine clinical evaluations in persons with MS, thereby leading to missed opportunities to optimize functional status and quality of life in patients with MS. A practical, systematic approach to the evaluation and treatment of sleep disorders in MS, in the co...
Source: Therapeutic Advances in Neurological Disorders - Category: Neurology Authors: Tags: Reviews Source Type: research
Conclusion:Presence of RLS seems to be the main factor determining poor sleep, fatigue, and daytime somnolence. Sleep disordered breathing and its severity influences only fatigue in patients with MS.Citation:Čarnická Z, Kollár B, Šiarnik P, Krížová L, Klobučníková K, Turčáni P. Sleep disorders in patients with multiple sclerosis. J Clin Sleep Med 2015;11(5):553–557.
Source: Journal of Clinical Sleep Medicine : JCSM - Category: Sleep Medicine Source Type: research
Abstract Sleep disorders are common in patients with multiple sclerosis (MS) and play a crucial role in health and quality of life; however, they are often overlooked. The most important sleep disorders in this context are as follows: insomnia, restless legs syndrome, periodic limb movement disorders, and sleep-related breathing disorders (SRBD). It is unclear if MS-related processes (lesions, brain atrophy) can cause symptomatic forms of sleep apnea. MS-related narcolepsy-like symptoms are described in the literature and, in some cases, have resolved with methylprednisolone pulse therapy. Similarly, REM sleep be...
Source: Current Neurology and Neuroscience Reports - Category: Neuroscience Source Type: research
• Questionnaire-based diagnosis of RLS in multiple sclerosis has a high false positive rate.• The high false positive rate is mostly due to multiple sclerosis-related sensorimotor symptoms.• The PLMI during wakefulness may provide useful diagnostic information.
Source: Sleep Medicine - Category: Sleep Medicine Authors: Tags: Original Article Source Type: research
Conclusion: This review suggests that seizure disorders and sleep disorders are common in MS, but highlights gaps in the epidemiological knowledge of these conditions in MS worldwide. Other than central-western Europe and North America, most regions are understudied.
Source: Multiple Sclerosis - Category: Neurology Authors: Tags: Systematic Review Source Type: research
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