Brief Report: Persistence of Non-Vaccine Oncogenic HPV Genotypes in Quadrivalent HPV-Vaccinated Women Living With HIV

Conclusions: qHPV-vaccinated WLWH continue to face a burden of persistent oncogenic HPV infection. Although the nonavalent vaccine could alleviate some of this burden, 2 of the top 3 persistent oncogenic HPVs in this cohort are not contained within any available vaccine. This highlights the need for ongoing cervical screening in HPV-vaccinated WLWH.
Source: JAIDS Journal of Acquired Immune Deficiency Syndromes - Category: Infectious Diseases Tags: Clinical Science Source Type: research

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AbstractPurposeTo describe knowledge about human papillomavirus (HPV), HPV-related care behavior, and advocacy intent (e.g., vaccine recommendation and willingness to become an advocate for vaccination) and to investigate associations between knowledge, HPV-related care behavior, and advocacy intent among HPV-related cancer survivors.MethodsA cross-sectional online survey was offered through Qualtrics to HPV-related  cancer survivors who were either volunteers at a cancer center or patients of survivorship clinics.ResultsA total of 200 survivors responded. Only 33.2% of respondents reported knowing their cancer was HP...
Source: Supportive Care in Cancer - Category: Cancer & Oncology Source Type: research
AbstractBackgroundFunctional somatic syndrome (FSS) is a disorder characterized by clusters of medically unexplained symptoms. Some women suffer from persistent FSS after human papillomavirus (HPV) vaccination. However, a causal relationship has not been established, and the pathophysiology of FSS remains elusive. Here, we aimed to identify the brain regions showing altered cerebral metabolism and neuroinflammation in patients with FSS and to correlate the measures of positron emission tomography (PET) with clinical data. Twelve women diagnosed with FSS following HPV vaccination (FSS group) underwent both [18F]FDG-PET to m...
Source: EJNMMI Research - Category: Radiology Source Type: research
Condition:   Dengue Fever Interventions:   Biological: 9vHPV vaccine;   Biological: Dengue Tetravalent Vaccine (TDV) Sponsor:   Takeda Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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Source: Human Vaccines and Immunotherapeutics - Category: Allergy & Immunology Authors: Source Type: research
The aim of the study was to determine whether supplementing a bundled recommendation (recommendation for all 11- to 12-year-old platform vaccines) with tailored messaging that addressed one versus all parental concerns improved human papillomavirus (HPV) vaccination intent among mothers.
Source: Journal of Adolescent Health - Category: Child Development Authors: Tags: Original article Source Type: research
Conclusion: Our study demonstrated an absence of clear association between HPV vaccines and autoimmune and other rare diseases. The review also highlights the need for more systematic collaborations to monitor rare safety adverse events.
Source: The Pediatric Infectious Disease Journal - Category: Infectious Diseases Tags: Original Studies Source Type: research
High-grade neuroendocrine carcinomas (HGNEC) of the cervix are rare and carry an extremely poor prognosis. Fortunately, there have been recent advances in our molecular understanding of these carcinomas and some advances offer novel therapeutic options. The vast majority of HGNEC of the cervix are associated with human papillomavirus (HPV) and would be prevented by currently available vaccines. TP53 mutations are variably identified and likely drive a second pathway, one unrelated to high-risk HPV.
Source: Diagnostic Histopathology - Category: Pathology Authors: Tags: Mini-symposium: Endocrine pathology Source Type: research
AbstractWe assessed the association of state legislation with  adolescent human papillomavirus (HPV) vaccination rates in states that legislated information dissemination or administration of HPV vaccination. Using insurance claims, we calculated monthly HPV vaccination rates (November 2009–December 2017) among adolescents in states that passed HPV vaccinat ion legislation during that period: Missouri (July 2010), Kentucky (February 2012), Indiana (March 2013), Oregon (June 2013). We used segmented regression to estimate levels and trends of HPV vaccination rates, comparing pre-legislation to post-legislation se...
Source: Journal of Community Health - Category: International Medicine & Public Health Source Type: research
Source: CDC Preventing Chronic Disease - Category: International Medicine & Public Health Tags: Public Health Source Type: news
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