Radiotherapy in Fibrodysplasia Ossificans Progressiva: A Case Report and Systematic Review of the Literature

In conclusion, available reports suggest no contraindication to radiotherapy in FOP patients; although the number of cases was small, systematic toxicity reports often were not available, and none of the reports described high-dose, high-energy radiation treatment at locations such as muscle and joint regions.
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research

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Authors: Park CH, Yang DH, Kim JW, Kim JH, Kim JH, Min YW, Lee SH, Bae JH, Chung H, Choi KD, Park JC, Lee H, Kwak MS, Kim B, Lee HJ, Lee HS, Choi M, Park DA, Lee JY, Byeon JS, Park CG, Cho JY, Lee ST, Chun HJ Abstract Although surgery was the standard treatment for early gastrointestinal cancers, endoscopic resection is now a standard treatment for early gastrointestinal cancers without regional lymph node metastasis. High-definition white light endoscopy, chromoendoscopy, and image-enhanced endoscopy such as narrow band imaging are performed to assess the edge and depth of early gastrointestinal cancers for deline...
Source: Clinical Endoscopy - Category: Gastroenterology Tags: Clin Endosc Source Type: research
Conclusion: Almost half of the population in the study use sunscreen. We have identified several areas of improper use of sunscreen. Increasing the awareness of effective sunscreen use in our community might be needed. PMID: 32256562 [PubMed]
Source: Dermatology Research and Practice - Category: Dermatology Tags: Dermatol Res Pract Source Type: research
The article by Naoum et  al1 was of great interest to us. The authors should be praised for their hard work on such a high-quality analysis. In the study, they found that the complication rates after postmastectomy radiation therapy were higher in the group that received a tissue expander/implant compared with the group t hat received direct-to-implant or autologous breast reconstruction. However, these results contradict those from a previous prospective randomized controlled study by Dikmans et al,2 which concluded that patients undergoing 1-stage immediate breast reconstruction were at a higher risk of adverse...
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Tags: Comments Source Type: research
We have read with interest the article by Qi et  al describing the results of a randomized trial testing 66 Gy versus 72 Gy for postoperative radiation therapy (RT) for prostate cancer with pathologic high-risk features (adjuvant RT) or biochemically recurrent prostate cancer patients after radical prostatectomy (salvage RT).1
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Tags: Comments Source Type: research
We read with great interest a prospective trial by Popotvzer et  al using a novel alpha-emitting brachytherapy source in the treatment of recurrent/unresectable squamous cell carcinoma of the skin and head/neck. This is a very challenging patient population, and we congratulate the investigators for developing this novel approach.
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Tags: Clinical Investigation Source Type: research
Sweden is one of the countries in the world with the highest 5-year survival rates for most cancers.1 Several important Swedish contributions in moving the field of radiation therapy (RT) forward worldwide have been made over the years, and there are hopefully many more to come. Although the number of modernly-equipped RT departments per number of inhabitants generally are well above other European countries (Table 1),2 there are challenges with recruiting and keeping staff, as well as organizational issues that affect patient waiting times.
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Tags: Feature Source Type: research
For stage IA, nonbulky, nodular lymphocyte-predominant Hodgkin lymphoma involving a single submental lymph node, the current standard of care is involved-site radiation therapy alone to a dose of 30 Gy in conventional fractionation. Retrospective series have shown excellent long-term outcome with radiation therapy (RT) alone. A  study from the German Hodgkin Study Group on stage I patients reported an 8-year progression-free survival (PFS) rate of 91.9% after involved-field radiation therapy.1 With positron emission tomography staging, and modern RT techniques to more limited volumes, the PFS rates and toxic...
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Tags: Gray Zone Source Type: research
Treatment approaches for nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) vary widely from observation to combined systemic therapy/radiation therapy (RT).1 Recommendations commonly depend on the disease burden at presentation. Prior studies including pediatric2 and adult3 patients have reported outcomes after observation of resected NLPHL and found 5-year event-free/progression-free survival rates of 77% and 59%, respectively, with no difference in overall survival for observed versus treated patients.
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Tags: Gray Zone Source Type: research
We describe a case of repeated lipotransfer into an atrophied reconstructed tongue.A 66-year-old patient with a squamous cell carcinoma of the tongue underwent hemiglossectomy and reconstruction of the tongue by a free radial forearm flap. After atrophy of the reconstructed tissue, repeated sessions of lipotransfer were undertaken to augment the atrophic tissue. Three sessions of lipotransfer resulted in satisfactory augmentation of the atrophied reconstructed tongue, leading to improvement of dysphagia and articulation.To our knowledge, this is the first report of lipotransfer used to augment a flap inside the oral cavity...
Source: Handchirurgie Mikrochirurgie Plastische Chirurgie - Category: Cosmetic Surgery Tags: Handchir Mikrochir Plast Chir Source Type: research
CONCLUSION: The DAM Science Academy can be considered a highly suitable complemental platform to the existing networking opportunities among microsurgical researchers. Experience so far suggests that this will hopefully result in long-term cooperations and a permanent transfer of knowledge among the participants. PMID: 32259860 [PubMed - in process]
Source: Handchirurgie Mikrochirurgie Plastische Chirurgie - Category: Cosmetic Surgery Tags: Handchir Mikrochir Plast Chir Source Type: research
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