Regulation of adipose tissue inflammation by interleukin 6 [Immunology and Inflammation]

Obesity is associated with a chronic state of low-grade inflammation and progressive tissue infiltration by immune cells and increased expression of inflammatory cytokines. It is established that interleukin 6 (IL6) regulates multiple aspects of metabolism, including glucose disposal, lipolysis, oxidative metabolism, and energy expenditure. IL6 is secreted by many tissues,...

Source: Proceedings of the National Academy of Sciences - February 10, 2020 Category: Science Authors: Myoung Sook Han, Alexis White, Rachel J. Perry, Joao-Paulo Camporez, Juan Hidalgo, Gerald I. Shulman, Roger J. Davis Tags: Inaugural Articles Biological Sciences Source Type: research