What does coal mine dust lung disease look like? A radiological review following re ‐identification in Queensland

ConclusionRadiological findings of particular interest included the high burden of opacities observed and the presence of RCS ‐associated features in the majority of subjects. Radiologists are at the front line in occupational lung disease screening/diagnosis and must be aware of the imaging spectrum.
Source: Journal of Medical Imaging and Radiation Oncology - Category: Radiology Authors: Tags: Medical Imaging —Original Article Source Type: research

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There is growing recognition for the involvement of blood vessels in pulmonary diseases beyond the classical scope of pulmonary vascular medicine. As an example, reports have described a vascular phenotype of COPD, or have proposed a vanishing pulmonary capillary syndrome to underly emphysema [1, 2]. Although the number of clinical and epidemiological studies supporting such a vascular hypothesis of pulmonary disease is steadily growing, biological underpinning in clinical studies remains to be provided.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Editorials Source Type: research
DiscussionWTC workers with spirometric low FVC have higher QCT-measured WAP compared to those with normal spirometries, but did not differ in distal airway and emphysema measurements, independently of obesity, smoking, and other covariates.
Source: Lung - Category: Respiratory Medicine Source Type: research
(Natural News) Chronic obstructive pulmonary disease (COPD) refers to a cluster of potentially fatal respiratory conditions. It is marked by breathlessness, inflammation, airway obstruction and significant bronchial damage. Many of the chronic respiratory diseases classified under COPD, such as emphysema and chronic bronchitis, are primarily caused by exposure to cigarette smoke. However, COPD can also...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
Chronic obstructive pulmonary disease (COPD) is a physiological diagnosis made on the basis of airflow obstruction. It develops when a genetically susceptible individual encounters sufficient inhaled environmental triggers. Genetic susceptibility is complex and determined by multiple alleles, with emphysema from α1-antitrypsin deficiency being a rare exception of well-described genetic risk. Cigarette smoke is the most common trigger in higher income countries, but globally the burning of biomass fuel in underventilated spaces is an important contributor to COPD.
Source: Medicine - Category: Internal Medicine Authors: Tags: Chronic obstructive lung disease Source Type: research
(Natural News) Chronic obstructive pulmonary disease (COPD) refers to a group of life-threatening diseases that severely affect the lungs, causing breathlessness, inflammation, airway obstruction and significant bronchial damage over time. Many of the chronic respiratory diseases classified under COPD are primarily caused by exposure to tobacco smoke, but they can also be exacerbated by factors such as air quality, existing cardiovascular...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
Rat bone mesenchymal stem cells exert antiproliferative effects on nicotine‑exposed T cells via iNOS production. Mol Med Rep. 2020 Mar 13;: Authors: Li X, Xu J, Li P Abstract Adoptive transfer of bone marrow‑derived mesenchymal stem cells (BMSCs) significantly alleviates smoking‑induced chronic obstructive pulmonary disease (COPD) in rats. Considering the critical roles of T cells during COPD development, the present study aimed to further identify the molecular mechanisms underlying the antiproliferative effect of BMSCs on splenic T cells isolated from rats following chronic exposure to nicotine...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
An artificial intelligence (AI) algorithm can provide fully automated quantification...Read more on AuntMinnie.comRelated Reading: From lab to clinic: How AI can help What issues are hindering AI's utility in radiology? Imaging shows rising scourge of black lung in coal miners Should CT be added to criteria for diagnosing COPD?
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
ConclusionOverall, our data show that GA effectively modulates pulmonary inflammation and emphysema associated with COPD pathogenesis in mice.
Source: Inflammation Research - Category: Research Source Type: research
Abstract Pulmonary emphysema is a major manifestation of chronic obstructive pulmonary disease and is associated with chronic pulmonary inflammation caused by cigarette smoking, with contributions from immune cells such as neutrophils, macrophages, and lymphocytes. Although matrix metalloproteinases are well-known to contribute to emphysema progression, the role of a disintegrin and metalloproteinase (ADAM) family proteins, other major metalloproteinases, in disease pathogenesis is largely unknown. ADAM17 is a major sheddase that cleaves various cell surface proteins, including CD62L, an adhesion molecule that pla...
Source: Am J Physiol Lung Ce... - Category: Respiratory Medicine Authors: Tags: Am J Physiol Lung Cell Mol Physiol Source Type: research
(Natural News) COPD, or chronic obstructive pulmonary disease, is an umbrella term referring to a group of progressive lung diseases. Among the common diseases classified under COPD are emphysema and chronic bronchitis. According to the American Lung Association, COPD is the third leading cause of death in the US, only behind cancer and heart disease....
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
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