Impact of Thyroid Autoimmunity on Ovarian Reserve, Pregnancy Outcomes, and Offspring Health in Euthyroid Women Following In Vitro Fertilization/Intracytoplasmic Sperm Injection

Thyroid, Ahead of Print.
Source: Thyroid - Category: Endocrinology Authors: Source Type: research

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Abstract This paper is a retrospective analysis of the sole transfer of monopronucleated zygotes (1PN) embryos both in in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) to determine the value of transferring embryos formed from 1PN. In fresh cycles, 1PN cleavage-stage embryos (1PN cleavage fresh) were transferred. In frozen-thawed cycles, 1PN blastocyst-stage embryos (1PN blast frozen) were transferred. We used comparison groups: for fresh cycles, 2PN cleavage-stage embryos (2PN cleavage fresh) were transferred; and for frozen-thawed cycles, 2PN blastocyst-stage embryos (2PN blast frozen) we...
Source: Zygote - Category: Reproduction Medicine Authors: Tags: Zygote Source Type: research
Conclusion: It is mandatory to point out that our conclusions are valid for patients with ovarian advanced endometriosis but normal ovarian functions. These results suggest three different progestins protocols are equivalent in terms of pregnancy outcomes for women with advanced endometriosis. PPOS protocol can be an alternative choice for women with severe endometriosis and normal ovarian reserve in IVF/ICSI treatment. These methods could be tested with other populations of women with endometriosis.Clinical Trial, identifier:ChiCTR-OIN-16008529.Trial registration date: 2014-05-25.Date o...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
ConclusionAMH-based stimulation has the same results of pregnancy rate and risk of OHSS and can reduce the dose of rFSH and duration of stimulation.
Source: Archives of Gynecology and Obstetrics - Category: OBGYN Source Type: research
ConclusionsThese findings indicate that there are no significant differences in the maturation of oocytes and the embryo quality for the women with low AMH level and ideal retrieval eggs but they should undergo IVF treatment and achieve successful pregnancy as soon as possible due to the higher basal FSH, the relatively fewer number of retrieval eggs and the possibility of coming diminished ovarian reserve (DOR) or poor respond (PR) despite their younger ages.
Source: Archives of Gynecology and Obstetrics - Category: OBGYN Source Type: research
Abstract INTRODUCTION: Antimullerian hormone (AMH) strongly correlates with ovarian reserve and response to controlled ovarian stimulation. Emerging data suggests that serum AMH level may also predict ART outcomes. However, AMH is characteristically elevated in PCOS women and it is unknown whether it may predict live birth outcomes in this population. METHODS: This was a retrospective cohort study of 184 PCOS women (Rotterdam criteria) who underwent their first fresh IVF/ICSI cycle. Women were divided into 3 groups according to the  75th (high) percentile of serum AMH concentration. Cycle stimulation p...
Source: Reproductive Biology - Category: Reproduction Medicine Authors: Tags: Reprod Biol Endocrinol Source Type: research
ConclusionOur study confirmed the essential role of PLCZ1 in fertilization and male fertility, which indicated the potential prognostic value of testing forPLCZ1 mutations in primary infertile men with sperm-derived fertilization failure.
Source: Journal of Assisted Reproduction and Genetics - Category: Reproduction Medicine Source Type: research
Publication date: Available online 4 March 2020Source: Saudi Journal of Biological SciencesAuthor(s): Songwei Jiang, Liuming Li, Feiwen Li, Mujun Li
Source: Saudi Journal of Biological Sciences - Category: Biology Source Type: research
Conditions:   Infertility;   Recurrent Implantation Failure;   Recurrent Miscarriage Intervention:   Sponsor:   Peking University Third Hospital Not yet recruiting
Source: - Category: Research Source Type: clinical trials
To investigate the impact of a history of previous naturally conceived tubal ectopic pregnancy (TEP) on subsequent IVF/intracytoplasmic sperm injection (ICSI) pregnancy and perinatal outcomes.
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: Original article Source Type: research
ConclusionsMutations in ciliopathy-relatedSPAG6 andRSPH3 cause severe asthenoteratospermia characterized by multiple flagellar malformations, resulting in sterility. ICSI is an optimal management with a positive pregnancy outcome.
Source: Journal of Assisted Reproduction and Genetics - Category: Reproduction Medicine Source Type: research
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