Peripheral biomarkers of mitochondrial dysfunction in adolescents with bipolar disorder

ConclusionThese preliminary results indicate that elevated lactate is observed even among adolescents early in their course of BD, that the association between lactate and ccf-mtDNA appears to be specific to BD, and that ccf-mtDNA is associated with depression symptoms in adolescent BD. In addition, the effect of psychotropic medications used in the treatment of BD on peripheral lactate and ccf-mtDNA requires further investigation.
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research