Partial oral antibiotic therapy is non-inferior to intravenous therapy in non-critically ill patients with infective endocarditis : Review and meta-analysis.

CONCLUSION: Data comparing POT with standard care in IE is limited and to date only one sufficiently powered stand-alone trial exists to support its use. In this meta-analysis POT was non-inferior to i.v. therapy with respect to mortality and IE relapse in non-critically ill patients suffering from both left-sided and right-sided IE. These findings indicate that POT is a feasible treatment strategy in selected patients suffering from IE but further validation in future studies will be required.
PMID: 32040621 [PubMed - as supplied by publisher]

Source: Wiener Klinische Wochenschrift - February 9, 2020 Category: General Medicine Authors: Rezar R, Jirak P, Lichtenauer M, Jung C, Lauten A, Hoppe UC, Wernly B Tags: Wien Klin Wochenschr Source Type: research