Campylobacter jejuni genes Cj1492c and Cj1507c are involved in host cell adhesion and invasion

ConclusionWe conclude that genes regulated by Cj1507c have an impact on efficient adhesion, invasion and intracellular survival ofC. jejuni in HT-29/B6 cells. Furthermore, potential signal sensing by Cj1492c seems to lead to limiting attachment and hence internalisation ofC. jejuni. However, as the intracellular survival capacities are reduced, we suggest that signal sensing by Cj1492c impacts several processes related to pathogenicity ofC. jejuni.
Source: Gut Pathogens - Category: Microbiology Source Type: research