Magnetic Resonance Texture Analysis in Alzheimer's disease

Publication date: Available online 10 February 2020Source: Academic RadiologyAuthor(s): Jia-Hui Cai, Yuan He, Xiao-Lin Zhong, Hao Lei, Fang Wang, Guang-Hua Luo, Heng Zhao, Jin-Cai LiuTexture analysis is an emerging field that allows mathematical detection of changes in MRI signals that are not visible among image pixels. Alzheimer's disease, a progressive neurodegenerative disease, is the most common cause of dementia. Recently, multiple texture analysis studies in patients with Alzheimer's disease have been performed. This review summarizes the main contributors to Alzheimer's disease-associated cognitive decline, presents a brief overview of texture analysis, followed by review of various MR imaging texture analysis applications in Alzheimer's disease. We also discuss the current challenges for widespread clinical utilization. MR texture analysis could potentially be applied to develop neuroimaging biomarkers for use in Alzheimer's disease clinical trials and diagnosis.
Source: Academic Radiology - Category: Radiology Source Type: research