Does Medicare ‐eligible high‐risk breast cancer screening MRI target the right women?

ConclusionsCancers were predominantly detected in women undergoing preoperative staging of new invasive lobular carcinoma in the contralateral breast, rather than the Medicare rebate ‐eligible high‐risk screening group.
Source: Journal of Medical Imaging and Radiation Oncology - Category: Radiology Authors: Tags: Medical Imaging —Original Article Source Type: research

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ConclusionConflicting evidences and lacking data about the benefits in terms of overall survival, disease-free survival and the long-term outcomes related to prophylactic bilateral mastectomy for CDH1 mutation carriers restrict the instruction for this type of procedure to selected cases, which should always be managed by a multidisciplinary team.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
ConclusionThis study illustrates the complementary benefits of mammography and BUS, especially where breast density is high. Tumours diagnosed by BUS alone had better prognostic features in terms of size, lymphovascular invasion, lymph node status, differentiation and hormone receptors, compared with cancers where all three modalities were positive.
Source: Australasian Radiology - Category: Radiology Authors: Tags: Medical Imaging —Original Article Source Type: research
AbstractPurposePleomorphic invasive lobular carcinoma (pILC) is a distinct morphological variant of ILC with a poorer prognosis than classical ILC (cILC). The aim of this study was to ascertain whether the conventional imaging appearances of the two entities differ.MethodsA single-center retrospective review of conventional imaging was undertaken in 150 consecutive patients with histopathologically confirmed ILC (38 pILC; 112 cILC) between April 2010 and July 2015. Mammographic and sonographic findings were evaluated using the BI-RADS lexicon by a radiologist blinded to pathology, and the findings in the two groups were co...
Source: Breast Cancer Research and Treatment - Category: Cancer & Oncology Source Type: research
CONCLUSION:  2 D SWE predicted lesion size more precisely than B-mode ultrasound or mammography. In cases of invasive lobular carcinoma, all three imaging methods underestimated lesion size, with 2 D SWE coming closest to the actual tumor size. PMID: 30125909 [PubMed - as supplied by publisher]
Source: Ultraschall in der Medizin - Category: Radiology Authors: Tags: Ultraschall Med Source Type: research
Authors: Chiorean AR, Szep MB, Feier DS, Duma M, Chiorean MA, Strilciuc Ș Abstract AIMS: The purpose of this study was to determine the impact of strain elastography (SE) on the Breast Imaging Reporting Data System (BI-RADS) classification depending on invasive lobular carcinoma (ILC) lesion size. MATERIALS AND METHODS: We performed a retrospective analysis on a sample of 152 female subjects examined between January 2010 - January 2017. SE was performed on all patients and ILC was subsequently diagnosed by surgical or ultrasound-guided biopsy. BI-RADS 1, 2, 6 and Tsukuba BGR cases were omitted. BI-RADS scores ...
Source: Medical Ultrasonography - Category: Radiology Tags: Med Ultrason Source Type: research
1056Objectives: Breast MRI is more sensitive for detecting breast cancer than other techniques as mammography or ultrasound, especially for nonpalpable lesions. The aim of this study is to evaluate usefulness of radioguided occult lesion localization (ROLL) and sentinel node and occult lesion localization (SNOLL) guided MRI in this clinical situation.Methods: In this retrospective study we included 32 newly diagnosed breast carcinoma patients. In all cases histological diagnosis was made by MRI-guided vacuum assisted biopsy A total of 48 lesions were marked with ROLL technique: 21 patients showed 1 lesion, 6 patients showe...
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Breast Cancer Posters Source Type: research
CONCLUSIONS: Pleomorphic histology, mass formation and BIRADS 5 category reflect more aggressive behaviour of LCIS and identify patients who need subsequent surgery. For other patients, close follow-up could be a safe alternative. PMID: 28507578 [PubMed]
Source: Archives of Medical Science - Category: Biomedical Science Tags: Arch Med Sci Source Type: research
ConclusionWe believe this preliminary study suggests that tomosynthesis is equivocal to MRI for assessing multifocality in ILC. If confirmed the implications would be a shorter investigative pathway with reduced delays and costs. A larger mutli-centre trial to assess the use of tomosynthesis to replace MRI in patients with ILC is warranted.Citation Format: Ironside A, Hawkesford K, Gomm J, Haywood L, Goulding I, Wang J, Lamaziere A, Poirot M, Silvente-Poirot S, Chelala C, Jones JL. Molecular mediators of mammographic density [abstract]. In: Proceedings of the Thirty-Ninth Annual CTRC-AACR San Antonio Breast Cancer Symposiu...
Source: Cancer Research - Category: Cancer & Oncology Authors: Tags: Poster Session Abstracts Source Type: research
Conclusion:This study has demonstrated that pre-operative MRI leads to additional investigations. Its impact on management is low if the lesion is mammographically occult but visible on ultrasound. In cases with ultrasound occult cancer and those with lobular features on core biopsy, it changes management in a significant proportion and should therefore be considered as a part of the diagnostic work-up.Citation Format: McGarrigle SA, Guinan EM, Hussey J, O'Sullivan J, Boyle T, Hanhauser Y, Al-azawi D, Kennedy MJ, Gallagher DJ, Connolly EM. Unhealthy lifestyle patterns are prevalent in unaffected BRCA mutation carriers 2016...
Source: Cancer Research - Category: Cancer & Oncology Authors: Tags: Poster Session Abstracts Source Type: research
CONCLUSION: MRI was most likely to show concordance with histopathology in the 'discordant assessment' and 'invasive lobular' groups and less likely for 'challenging clinically dense breast tissue.' MRI changed management in 69/181 (38.1%). PMID: 28187373 [PubMed - as supplied by publisher]
Source: Breast - Category: Cancer & Oncology Authors: Tags: Breast Source Type: research
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