Pancreatic anti-GP2 and anti-Saccharomyces cerevisiae antibodies in ruminants with paratuberculosis: A better understanding of the immunopathogenesis of Crohn's disease.

CONCLUSION: ASCA are present in a significant proportion of ruminants with ptb and correlate with anti-GP2 antibody positivity, a finding further supporting the notion that Crohn's disease and ptb share common immunological mechanisms of antigen-driven loss of self-tolerance. PMID: 32035824 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32035824?dopt=Abstract

Source: Clin Med Res - February 4, 2020 Category: Research Authors: Liaskos C, Gkoutzourelas A, Spyrou V, Koutsoumpas A, Athanasiou LV, Amiridis GS, Billinis C, Bogdanos DP Tags: Clin Res Hepatol Gastroenterol Source Type: research