NF- κB-dependent Mechanism of Action of c-Myc Inhibitor 10058-F4: Highlighting a Promising ...

In conclusion, the results of the present study shed light on the favorable anti-leukemic effect of 10058-F4, especially in combination with PI3K inhibitors in acute promyelocytic leukemia; however, further investigations should be accomplished to determine the efficacy of the inhibitor, either as a single agent or in a combined-modal strategy, in leukemia treatment.
Source: Iranian Journal of Pharmaceutical Research - Category: Drugs & Pharmacology Source Type: research