Eplerenone enhances cardioprotective effects of standard heart failure therapy through matricellular proteins in hypertensive heart failure

Conclusion:In a hypertensive heart failure rat model, the addition of eplerenone to conventional heart failure therapy further improves cardiac structural and functional parameters, delaying the progression of heart failure. These beneficial effects of eplerenone were associated with normalization of matricellular protein expression.
Source: Journal of Hypertension - Category: Cardiology Tags: ORIGINAL PAPERS: Therapeutic aspects Source Type: research