Fasting glucagon concentrations are associated with longitudinal decline of β-cell function in non-diabetic humans
Abnormal glucagon concentrations are a feature of prediabetes but it is uncertain if α-cell dysfunction contributes to a longitudinal decline in β-cell function. We therefore sought to determine if a decline in β-cell function is associated with a higher nadir glucagon in the postprandial period or with higher fasting glucagon.
Source: Metabolism - Clinical and Experimental - Category: Biomedical Science Authors: Jon D. Adams, Chiara Dalla Man, Marcello C. Laurenti, M. Daniela Hurtado Andrade, Claudio Cobelli, Robert A. Rizza, Kent R. Bailey, Adrian Vella Tags: Brief Report Source Type: research