High Incidence of Clonal CD8+ T-cell Proliferation in Non-malignant Conditions May Reduce the Significance of T-cell Clonality Assay for Differential Diagnosis in Oncohematology

The objective of this study was to evaluate the specificity and positive predictive value of PCR-based clonality assessment for a differential diagnostics of T-LGL leukemia.

Source: Clinical Lymphoma, Myeloma and Leukemia - January 7, 2020 Category: Hematology Authors: Yulia V. Sidorova, Kseniya A. Sychevskaya, Nataliya G. Chernova, Hunan L. Julhakyan, Svetlana Ju. Smirnova, Nataliya V. Ryzhikova, Vadim R. Gorodetskiy, Elena V. Naumova, Andrey B. Sudarikov Tags: Review Source Type: research