The allergen Mus m 1.0102: Cysteine residues and molecular allergology

We report that, among the tested mutants, C138A mutant acquires a structure more resistant to thermal stress and less prone to aggregation, two events that act positively on the protein shelf life. Those features make that MUP variant an attractive lead molecule for the development of a diagnostic kit and/or a vaccine.
Source: Molecular Immunology - Category: Allergy & Immunology Source Type: research