Randomized phase II/III study of 5-fluorouracil/ l -leucovorin versus 5-fluorouracil/ l -leucovorin plus paclitaxel administered to patients with severe peritoneal metastases of gastric cancer (JCOG1108/WJOG7312G)

ConclusionsChemotherapy was indicated for patients with severe peritoneal metastases excluding patients with PS 2 having massive ascites and inadequate oral intake simultaneously. FLTAX did not confer a significant survival benefit but may be preferred because of longer PFS and acceptable toxicity.

http://link.springer.com/10.1007/s10120-020-01043-x

Source: Gastric Cancer - February 7, 2020 Category: Gastroenterology Source Type: research